nitrocefin

Known as: (6R-(3(E),6 alpha,7 beta))-3-(2-(2,4-dinitrophenyl)ethenyl)-8-oxo-7-((2-thienylacetyl)amino)- 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(2,4-Dinitrostyryl)-(6R, 7R)-7-(2-thienylacetamido)-ceph-3-em-4-carboxylic Acid 
A beta-lactam antibiotic, with diagnostic properties. Nitrocefin is sensitive to hydrolysis by all lactamases produced by gram-positive and gram… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The AcrB trimeric multidrug efflux transporter of Escherichia coli pumps out a very wide spectrum of compounds. Although… (More)
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2009
2009
The realization that majority of microbes are not amenable to cultivation as isolates under laboratory conditions has led to the… (More)
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2007
2007
The hydrolysis of the β-lactam compound nitrocefin by the metallo-β-lactamase from B.cereus (BcII) was studied by pre-steady… (More)
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2005
2005
Nitrocefin is a key reagent for high and low throughput assays of the activities of penicillin-binding proteins (PBPs) and beta… (More)
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Highly Cited
2004
Highly Cited
2004
Two allosteric enzymes have been created by the covalent linkage of non-interacting, monomeric proteins with the prerequisite… (More)
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2001
2001
The diverse members of the metallo-beta-lactamase family are a growing clinical threat evolving under considerable selective… (More)
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Highly Cited
1991
Highly Cited
1991
In Streptomyces coelicolor A3(2) and the related species Streptomyces lividans 66, aerial mycelium formation and antibiotic… (More)
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1990
1990
We describe a nitrocefin competition assay for determining inhibition profiles as a useful adjunct to existing biochemical… (More)
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Highly Cited
1984
Highly Cited
1984
Hydrolysis of the chromogenic beta-lactam nitrocefin by periplasmic beta-lactamase in intact Pseudomonas aeruginosa cells was… (More)
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Highly Cited
1982
Highly Cited
1982
The Pseudomonas aeruginosa mutant Z61 has been shown to be highly supersusceptible to a wide range of antibiotics, including beta… (More)
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