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Ceftriaxone

Known as: Ceftriaxon, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R-(6alpha,7beta(Z)))- 
A beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Ceftriaxone binds to and inactivates penicillin-binding proteins… 
National Institutes of Health

Papers overview

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Highly Cited
2020
Highly Cited
2020
Importance In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of… 
Highly Cited
2012
Highly Cited
2012
OBJECTIVES The aim of this study was to characterize the first two extended-spectrum cephalosporin-resistant and multidrug… 
Highly Cited
2011
Highly Cited
2011
ABSTRACT Recently, the first Neisseria gonorrhoeae strain (H041) highly resistant to the expanded-spectrum cephalosporins (ESCs… 
Review
2009
Review
2009
  • G. Jacoby
  • Clinical Microbiology Reviews
  • 2009
  • Corpus ID: 25382533
SUMMARY AmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae… 
Highly Cited
2007
Highly Cited
2007
It takes too long and costs too much to bring new drugs to market. So let's beef up efforts to screen existing drugs for new uses… 
Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS Oral norfloxacin is the standard of therapy in the prophylaxis of bacterial infections in cirrhotic patients… 
Highly Cited
2005
Highly Cited
2005
Glutamate is the principal excitatory neurotransmitter in the nervous system. Inactivation of synaptic glutamate is handled by… 
Highly Cited
2000
Highly Cited
2000
BACKGROUND The emergence of resistance to antimicrobial agents within the salmonellae is a worldwide problem that has been… 
Highly Cited
2000
Highly Cited
2000
CONTEXT Ceftriaxone, an expanded-spectrum cephalosporin, is an antimicrobial agent commonly used to treat severe Salmonella… 
Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of…