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Ceftriaxone
Known as:
Ceftriaxon
, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R-(6alpha,7beta(Z)))-
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A beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Ceftriaxone binds to and inactivates penicillin-binding proteins…
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National Institutes of Health
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Related topics
Related topics
40 relations
Broader (1)
Anti-Bacterial Agents
Bacterial Infections
Bone Diseases, Infectious
Ceftriaxone 1000 MG Injection
Ceftriaxone:MCnc:Pt:Ser/Plas:Qn
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Narrower (6)
Ceftriaxona Andreu
Ceftriaxone Irex
Ceftriaxone Sodium
Longacef
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang
,
Bo Hu
,
+11 authors
Z. Peng
JAMA
2020
Corpus ID: 211050495
Importance In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of…
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Highly Cited
2012
Highly Cited
2012
Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain.
J. Càmara
,
J. Serra
,
+4 authors
C. Ardanuy
The Journal of antimicrobial chemotherapy
2012
Corpus ID: 205149076
OBJECTIVES The aim of this study was to characterize the first two extended-spectrum cephalosporin-resistant and multidrug…
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Highly Cited
2011
Highly Cited
2011
High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure
M. Unemo
,
D. Golparian
,
R. Nicholas
,
M. Ohnishi
,
A. Gallay
,
P. Sednaoui
Antimicrobial Agents and Chemotherapy
2011
Corpus ID: 11942651
ABSTRACT Recently, the first Neisseria gonorrhoeae strain (H041) highly resistant to the expanded-spectrum cephalosporins (ESCs…
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Review
2009
Review
2009
AmpC β-Lactamases
G. Jacoby
Clinical Microbiology Reviews
2009
Corpus ID: 25382533
SUMMARY AmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae…
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Highly Cited
2007
Highly Cited
2007
New uses for old drugs
C. Chong
,
D. Sullivan
Nature
2007
Corpus ID: 154688
It takes too long and costs too much to bring new drugs to market. So let's beef up efforts to screen existing drugs for new uses…
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Highly Cited
2006
Highly Cited
2006
Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage.
Javier Fernández
,
L. Ruiz del Arbol
,
+6 authors
M. Navasa
Gastroenterology
2006
Corpus ID: 28279742
BACKGROUND & AIMS Oral norfloxacin is the standard of therapy in the prophylaxis of bacterial infections in cirrhotic patients…
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Highly Cited
2005
Highly Cited
2005
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
J. Rothstein
,
S. Patel
,
+12 authors
P. Fisher
Nature
2005
Corpus ID: 4301666
Glutamate is the principal excitatory neurotransmitter in the nervous system. Inactivation of synaptic glutamate is handled by…
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Highly Cited
2000
Highly Cited
2000
Ceftriaxone-resistant salmonella infection acquired by a child from cattle.
P. Fey
,
T. Safranek
,
+6 authors
S. Hinrichs
The New England journal of medicine
2000
Corpus ID: 16983336
BACKGROUND The emergence of resistance to antimicrobial agents within the salmonellae is a worldwide problem that has been…
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Highly Cited
2000
Highly Cited
2000
Emergence of domestically acquired ceftriaxone-resistant Salmonella infections associated with AmpC beta-lactamase.
E. Dunne
,
P. Fey
,
+12 authors
F. Angulo
JAMA
2000
Corpus ID: 26086691
CONTEXT Ceftriaxone, an expanded-spectrum cephalosporin, is an antimicrobial agent commonly used to treat severe Salmonella…
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Highly Cited
1988
Highly Cited
1988
Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.
V. Jarlier
,
M. Nicolas
,
G. Fournier
,
A. Philippon
Reviews of infectious diseases
1988
Corpus ID: 21938834
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of…
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