Ceftriaxone

Known as: Ceftriaxon, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R-(6alpha,7beta(Z)))- 
A beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Ceftriaxone binds to and inactivates penicillin-binding proteins… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Recently, the first Neisseria gonorrhoeae strain (H041) highly resistant to the expanded-spectrum cephalosporins (ESCs… (More)
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Highly Cited
2012
Highly Cited
2012
OBJECTIVES The aim of this study was to characterize the first two extended-spectrum cephalosporin-resistant and multidrug… (More)
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Highly Cited
2011
Highly Cited
2011
Recently, the first Neisseria gonorrhoeae strain (H041) that is highly resistant to the extended-spectrum cephalosporin (ESC… (More)
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Highly Cited
2011
Highly Cited
2011
To the Editor: Spread of multi-drug-resistant Neisseria gonorrhoeae is a major public health concern. Effective antimicrobial… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The cystine-glutamate exchanger is downregulated after chronic cocaine, resulting in reduced extracellular levels of… (More)
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Highly Cited
2008
Highly Cited
2008
Glutamate is an essential neurotransmitter regulating brain functions. Excitatory amino acid transporter (EAAT)-2 is one of the… (More)
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Highly Cited
2007
Highly Cited
2007
The recent emergence and transmission of Neisseria gonorrhoeae isolates with reduced susceptibility to expanded-spectrum… (More)
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Highly Cited
2005
Highly Cited
2005
Glutamate is the principal excitatory neurotransmitter in the nervous system. Inactivation of synaptic glutamate is handled by… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The emergence of resistance to antimicrobial agents within the salmonellae is a worldwide problem that has been… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT Ceftriaxone, an expanded-spectrum cephalosporin, is an antimicrobial agent commonly used to treat severe Salmonella… (More)
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