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Ceftriaxone

Known as: Ceftriaxon, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R-(6alpha,7beta(Z)))- 
A beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Ceftriaxone binds to and inactivates penicillin-binding proteins… Expand
National Institutes of Health

Papers overview

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Highly Cited
2020
Highly Cited
2020
Importance In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of… Expand
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Review
2018
Review
2018
Pectin is a polymer with a core of alternating α-1,4-linked d-galacturonic acid and α-1,2-l-rhamnose units, as well as a variety… Expand
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Highly Cited
2011
Highly Cited
2011
ABSTRACT Recently, the first Neisseria gonorrhoeae strain (H041) that is highly resistant to the extended-spectrum cephalosporin… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The cystine-glutamate exchanger is downregulated after chronic cocaine, resulting in reduced extracellular levels of… Expand
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Highly Cited
2007
Highly Cited
2007
It takes too long and costs too much to bring new drugs to market. So let's beef up efforts to screen existing drugs for new uses… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS Oral norfloxacin is the standard of therapy in the prophylaxis of bacterial infections in cirrhotic patients… Expand
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Highly Cited
2005
Highly Cited
2005
Glutamate is the principal excitatory neurotransmitter in the nervous system. Inactivation of synaptic glutamate is handled by… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The emergence of resistance to antimicrobial agents within the salmonellae is a worldwide problem that has been… Expand
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Highly Cited
1992
Highly Cited
1992
STUDY OBJECTIVE To determine the outcome of outpatient treatment of febrile infants 28 to 89 days of age with intramuscular… Expand
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Highly Cited
1988
Highly Cited
1988
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… Expand
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