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Ceftriaxone

Known as: Ceftriaxon, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R-(6alpha,7beta(Z)))- 
A beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Ceftriaxone binds to and inactivates penicillin-binding proteins… 
National Institutes of Health

Related topics

Related topics

40 relations

Broader (1)

Anti-Bacterial Agents
Bacterial InfectionsBone Diseases, InfectiousCeftriaxone 1000 MG InjectionCeftriaxone:MCnc:Pt:Ser/Plas:Qn
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Narrower (6)

Ceftriaxona AndreuCeftriaxone IrexCeftriaxone SodiumLongacef
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Importance In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China. The number of… 
Highly Cited
2012
Highly Cited
2012
Molecular characterization of two high-level ceftriaxone-resistant Neisseria gonorrhoeae isolates detected in Catalonia, Spain.
OBJECTIVES The aim of this study was to characterize the first two extended-spectrum cephalosporin-resistant and multidrug… 
Highly Cited
2011
Highly Cited
2011
High-Level Cefixime- and Ceftriaxone-Resistant Neisseria gonorrhoeae in France: Novel penA Mosaic Allele in a Successful International Clone Causes Treatment Failure
ABSTRACT Recently, the first Neisseria gonorrhoeae strain (H041) highly resistant to the expanded-spectrum cephalosporins (ESCs… 
Review
2009
Review
2009
AmpC β-Lactamases
  • G. Jacoby
  • Clinical Microbiology Reviews
  • 2009
  • Corpus ID: 25382533
SUMMARY AmpC β-lactamases are clinically important cephalosporinases encoded on the chromosomes of many of the Enterobacteriaceae… 
Highly Cited
2007
Highly Cited
2007
New uses for old drugs
It takes too long and costs too much to bring new drugs to market. So let's beef up efforts to screen existing drugs for new uses… 
Highly Cited
2006
Highly Cited
2006
Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage.
BACKGROUND & AIMS Oral norfloxacin is the standard of therapy in the prophylaxis of bacterial infections in cirrhotic patients… 
Highly Cited
2005
Highly Cited
2005
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
Glutamate is the principal excitatory neurotransmitter in the nervous system. Inactivation of synaptic glutamate is handled by… 
Highly Cited
2000
Highly Cited
2000
Ceftriaxone-resistant salmonella infection acquired by a child from cattle.
BACKGROUND The emergence of resistance to antimicrobial agents within the salmonellae is a worldwide problem that has been… 
Highly Cited
2000
Highly Cited
2000
Emergence of domestically acquired ceftriaxone-resistant Salmonella infections associated with AmpC beta-lactamase.
CONTEXT Ceftriaxone, an expanded-spectrum cephalosporin, is an antimicrobial agent commonly used to treat severe Salmonella… 
Highly Cited
1988
Highly Cited
1988
Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.
Before 1985 at the Pitié-Salpêtrière Hospital in Paris (2,400 beds), resistance to cefotaxime in clinical isolates of… 
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