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Ceftriaxone

Known as: Ceftriaxon, (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-, (6R-(6alpha,7beta(Z)))- 
A beta-lactam, third-generation cephalosporin antibiotic with bactericidal activity. Ceftriaxone binds to and inactivates penicillin-binding proteins… 
National Institutes of Health

Related topics

Related topics

40 relations

Broader (1)

Anti-Bacterial Agents
Bacterial InfectionsBone Diseases, InfectiousCeftriaxone 1000 MG InjectionCeftriaxone:MCnc:Pt:Ser/Plas:Qn

Narrower (6)

Ceftriaxona AndreuCeftriaxone IrexCeftriaxone SodiumLongacef

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
RESISTANCE PATTERN OF CLINICAL ISOLATES OF STAPHYLOCOCCUS AUREUS AGAINST FIVE GROUPS OF ANTIBIOTICS
Among the samples received in pathology laboratory, Pakistan Institute of Medical Sciences, Islamabad, 5069 samples had bacterial… 
1998
1998
Acute hepatitis, autoimmune hemolytic anemia, and erythroblastocytopenia induced by ceftriaxone
An 80-yr-old man developed acute hepatitis shortly after ingesting oral ceftriaxone. Although the transaminases gradually… 
1989
1989
Ceftriaxone-netilmicin combination in single-daily-dose treatment of experimental Escherichia coli endocarditis
We evaluated the activities of ceftriaxone (15 mg/kg), netilmicin (6 mg/kg), and their combination given intramuscularly once… 
Highly Cited
1987
Highly Cited
1987
Value of antibiotic levels in serum and cardiac vegetations for predicting antibacterial effect of ceftriaxone in experimental Escherichia coli endocarditis
In a rabbit model of Escherichia coli endocarditis, we studied the penetration into infected vegetations and the antibacterial… 
1985
1985
Ceftriaxone therapy in bacteremic typhoid fever
The efficacy and safety of ceftriaxone in the treatment of bacteremic typhoid fever was studied in 14 patients. Ceftriaxone at a… 
Highly Cited
1984
Highly Cited
1984
Pharmacokinetics of ceftriaxone in patients with renal and liver insufficiency and correlations with a physiologic nonlinear protein binding model.
In patients with normal hepatic and renal function, between 30 and 60 percent of administered ceftriaxone is eliminated by… 
1984
1984
Kinetic disposition of intravenous ceftriaxone in normal subjects and patients with renal failure on hemodialysis or peritoneal dialysis
The kinetic disposition of a single intravenous dose of ceftriaxone (250 to 665 mg) was studied in six normal subjects and nine… 
1983
1983
Comparative study of ceftriaxone and aqueous procaine penicillin G in the treatment of uncomplicated gonorrhea in women
Uncomplicated gonorrhea of 122 mucosal sites in 51 women was successfully treated with either a single intramuscular dose of 250… 
1982
1982
Comparative in vitro activity of ceftriaxone against anaerobic bacteria
The in vitro activity of ceftriaxone was compared with those of other recently introduced beta-lactam antimicrobial agents… 
1982
1982
Comparative efficacies of ceftriaxone, moxalactam, and ampicillin in experimental Salmonella typhimurium infection
The activities of ceftriaxone, moxalactam, and ampicillin against Salmonella typhimurium LT-2 were compared in culture media at… 
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