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nimetazepam
Known as:
1-methyl-7-nitro-5-phenyl-1,3-dihydro-2H-1,4- benzodiazepin-2-one
National Institutes of Health
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Related topics
Related topics
8 relations
Broader (5)
Anti-Anxiety Agents
Anticonvulsants
GABA Modulators
Hypnotics and Sedatives
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Narrower (2)
Hypnon
S-1530
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Simultaneous determination of designer benzodiazepines in human serum using non-aqueous capillary electrophoresis - Tandem mass spectrometry with successive multiple ionic - Polymer layer coated…
Martin Švidrnoch
,
Barbora Boráňová
,
J. Tomková
,
P. Ondra
,
V. Maier
Talanta
2018
Corpus ID: 45768793
A novel non-aqueous capillary electrophoresis - tandem mass spectrometry method for the simultaneous separation, identification…
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2017
2017
Analysis of selected designer benzodiazepines by ultra high performance liquid chromatography with high-resolution time-of-flight mass spectrometry and the estimation of their partition coefficients…
J. Tomková
,
Martin Švidrnoch
,
V. Maier
,
P. Ondra
Journal of separation science
2017
Corpus ID: 5470784
A new ultra high performance liquid chromatography with electrospray ionization time of flight mass spectrometry method for the…
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2013
2013
Simultaneous quantification of urine flunitrazepam, nimetazepam and nitrazepam by using liquid chromatography tandem mass spectrometry.
Hei Hwa Lee
,
Jong Feng Lee
,
+4 authors
B. H. Chen
Clinica chimica acta; international journal of…
2013
Corpus ID: 11865091
BACKGROUND Benzodiazepines are used in hypnotics, sedation, and anti-anxiety. Recently liquid chromatography tandem mass…
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2013
2013
Determination of nimetazepam and 7-aminonimetazepam in human urine by using liquid chromatography-tandem mass spectrometry.
Kuang-Chuan Wang
,
M. Cheng
,
Chin-Lin Hsieh
,
Jung-Fa Hsu
,
Jen-Der Wu
,
Ching-Kuo Lee
Forensic science international
2013
Corpus ID: 2663275
We report determination of metabolites of popular drugs of abuse, including nimetazepam and nitrazepam, in urine by using liquid…
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Highly Cited
2010
Highly Cited
2010
Development and validation of an EI-GC-MS method for the determination of benzodiazepine drugs and their metabolites in blood: applications in clinical and forensic toxicology.
I. Papoutsis
,
S. Athanaselis
,
Panagiota Nikolaou
,
C. Pistos
,
C. Spiliopoulou
,
Constantinos P Maravelias
Journal of pharmaceutical and biomedical analysis
2010
Corpus ID: 23250511
Benzodiazepines are used widely in daily clinical practice, due to their multiple pharmacological actions. The frequent problems…
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2009
2009
Metabolic Activation of Benzodiazepines by CYP3A4
K. Mizuno
,
M. Katoh
,
+5 authors
Tsuyoshi Yokoi
Drug Metabolism and Disposition
2009
Corpus ID: 5688931
Cytochrome P450 3A4 is the predominant isoform in liver, and it metabolizes more than 50% of the clinical drugs commonly used…
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2004
2004
The Quantitation of Nimetazepam in Erimin-5 Tablets and Powders by Reverse-Phase HPLC
Y. K. Chong
,
Muzaiyanah Mohd Kaprawi
,
Kee Bian Chan
2004
Corpus ID: 96569195
The sedative-hypnotic nimetazepam in "Erimin 5" tablets and powders was quantitated by reverse phase HPLC. The selectivity…
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1999
1999
Solid-phase microextraction and GC-ECD of benzophenones for detection of benzodiazepines in urine.
F. Guan
,
H. Seno
,
+4 authors
O. Suzuki
Journal of analytical toxicology
1999
Corpus ID: 38718930
Benzodiazepines are common drugs that cause intoxication. Benzodiazepines and their metabolites can be converted by hydrolysis in…
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1980
1980
Reversible ring-opening reactions of nimetazepam and nitrazepam in acidic media at body temperature.
N. Inotsume
,
M. Nakano
Journal of pharmaceutical sciences
1980
Corpus ID: 36062832
Hydrolytic reactions of nimetazepam and nitrazepam in acidic solutions at body temperature were studied spectrophotometrically…
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1976
1976
Comparative metabolic study of nimetazepam and its desmethyl derivative (nitrazepam) in dogs.
Y. Yanagi
,
F. Haga
,
M. Endo
,
S. Kitagawa
Xenobiotica; the fate of foreign compounds in…
1976
Corpus ID: 24331658
1. Blood levels of nimetazepam after oral administration to dogs were relatively low at early periods after dosage and reached…
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