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nicotine dehydrogenase activity

Known as: nicotine:(acceptor) 6-oxidoreductase (hydroxylating), nicotine oxidase activity, D-nicotine oxidase activity 
Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor. [EC:1.5.99.4]
National Institutes of Health

Papers overview

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2019
2019
BackgroundFlavonol synthase (FLS) is the key enzyme responsible for the biosynthesis of flavonols, the most abundant flavonoids… Expand
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2013
2013
Nicotine metabolism is believed to affect not only nicotine’s pharmacological effects but also nicotine addiction. As a key step… Expand
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Highly Cited
2002
Highly Cited
2002
The purpose of the study was to elucidate human intestinal cytochrome P450 isoform(s) involved in the metabolism of an… Expand
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2001
2001
The purpose of the study was to elucidate human intestinal cytochrome P450 isoform(s) involved in the metabolism of an… Expand
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Highly Cited
1994
Highly Cited
1994
Acute toxicity of nicotine was examined in old (24 months) and young (6 weeks) Wistar rats. There were no significant age… Expand
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1990
1990
Rabbit lung microsomes metabolize (S)-nicotine primarily to (S)-nicotine delta 1',5'-iminium ion, which is the precursor of (S… Expand
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1982
1982
When rats were pretreated with 3-methylcholanthrene of beta-naphthoflavone, hepatic nicotine oxidase activity per cytochrome P… Expand
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1982
1982
The induction by d,l-nicotine of the enantiozymes 6-hydroxy-L-nicotine oxidase and 6-hydroxy-D-nicotine oxidase in Archrobacter… Expand
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1977
1977
The localization of three monooxygenase (hydroxylase) enzyme systems which occur in dark-grown seedlings of Sorghum bicolor has… Expand
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1971
1971
Abstract The mechanism of the return to normal of the elevated urinary catecholamines observed after the chronic administration… Expand
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