Skip to search formSkip to main contentSkip to account menu

neutral sphingomyelin phosphodiesterase activity

Known as: neutral SMase, neutral sphingomyelinase 
Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment. [GOC:dph, PMID:26493087]
National Institutes of Health

Related topics

Related topics

1 relation
Sphingomyelin Phosphodiesterase 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Acid and Neutral Sphingomyelinase Behavior in Radiation-Induced Liver Pyroptosis and in the Protective/Preventive Role of rMnSOD
Sphingomyelins (SMs) are a class of relevant bioactive molecules that act as key modulators of different cellular processes, such… 
2019
2019
Neutral Sphingomyelinase Modulation in the Protective/Preventive Role of rMnSOD from Radiation-Induced Damage in the Brain
Studies on the relationship between reactive oxygen species (ROS)/manganese superoxide dismutase (MnSOD) and sphingomyelinase… 
2014
2014
Effect of Procysteine on aging-associated changes in hepatic GSH and SMase: evidence for transcriptional regulation of smpd3[S]
In hepatocytes, aging-associated decline in GSH has been linked to activation of neutral SMase (nSMase), accumulation of… 
2011
2011
Temporal expression profiles of ceramide and ceramide-related genes in wild-type and mPer1/mPer2 double knockout mice
Most living organisms exhibit circadian rhythms in physiology and behavior. These oscillations are generated by an endogenous… 
Review
2009
Review
2009
[Structure and function of sphingomyelinase].
  • M. Oda
  • Yakugaku zasshi : Journal of the Pharmaceutical…
  • 2009
  • Corpus ID: 28234885
Bacillus cereus is one that causes of opportunistic human infections. Sphingomyelinase produced by B. cereus is assumed a… 
Highly Cited
2006
Highly Cited
2006
Structural Basis of the Sphingomyelin Phosphodiesterase Activity in Neutral Sphingomyelinase from Bacillus cereus*
Sphingomyelinase (SMase) from Bacillus cereus (Bc-SMase) hydrolyzes sphingomyelin to phosphocholine and ceramide in a divalent… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)