negative regulation of production of siRNA involved in RNA interference

Known as: negative regulation of RNA interference, production of guide RNAs, down-regulation of RNA interference, production of guide RNAs, down regulation of production of siRNA involved in RNA interference 
Any process that stops, prevents or reduces the frequency, rate or extent of production of siRNA involved in RNA interference. [GO_REF:0000058, GOC… (More)
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Monomeric CRISPR-Cas9 nucleases are widely used for targeted genome editing but can induce unwanted off-target mutations with… (More)
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Highly Cited
2014
Highly Cited
2014
Identification of genes influencing a phenotype of interest is frequently achieved through genetic screening by RNA interference… (More)
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Highly Cited
2014
Highly Cited
2014
RNA-based regulation and CRISPR/Cas transcription factors (CRISPR-TFs) have the potential to be integrated for the tunable… (More)
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Highly Cited
2013
Highly Cited
2013
Short guide RNAs (gRNAs) can direct catalytically inactive CRISPR-associated 9 nuclease (dCas9) to repress endogenous genes in… (More)
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Highly Cited
2013
Highly Cited
2013
Precise and straightforward methods to edit the plant genome are much needed for functional genomics and crop improvement… (More)
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Highly Cited
2006
Highly Cited
2006
Micro RNAs (miRNAs) regulate gene expression at the posttranscriptional level. Here we show that regulatory T (T reg) cells have… (More)
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Highly Cited
2006
Highly Cited
2006
Micro RNAs (miRNAs) are approximately 22 nucleotide single-stranded noncoding RNA molecules that bind to target messenger RNAs… (More)
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Highly Cited
2004
Highly Cited
2004
Micro-RNAs (miRNAs) are small, noncoding RNAs of 18-25 nt in length that negatively regulate their complementary mRNAs at the… (More)
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Highly Cited
2003
Highly Cited
2003
Influenza A virus causes widespread infection in the human respiratory tract, but existing vaccines and drug therapy are of… (More)
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Highly Cited
2002
Highly Cited
2002
Two major classes of small noncoding RNAs have emerged as important regulators of gene expression in eukaryotes, the short… (More)
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