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negative regulation of histone H3-K27 acetylation

Known as: inhibition of histone H3 acetylation at K27, downregulation of histone H3K27 acetylation, down regulation of histone H3K27 acetylation 
Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 acetylation. [GOC:BHF, GOC:TermGenie]
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Histone methyltransferases and demethylases reversibly modulate histone lysine methylation, which is considered a key epigenetic… Expand
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Highly Cited
2014
Highly Cited
2014
G9a/GLP and Polycomb Repressive Complex 2 (PRC2) are two major epigenetic silencing machineries, which in particular methylate… Expand
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Highly Cited
2013
Highly Cited
2013
Whether osteoarthritis (OA) is associated with alterations in the epigenetic status of anabolic factors is largely unknown. To… Expand
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Highly Cited
2013
Highly Cited
2013
The symptoms of ataxia-telangiectasia (A-T) include a progressive neurodegeneration caused by ATM protein deficiency. We… Expand
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Highly Cited
2012
Highly Cited
2012
UTX (KDM6A) and UTY are homologous X and Y chromosome members of the Histone H3 Lysine 27 (H3K27) demethylase gene family. UTX… Expand
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Highly Cited
2011
Highly Cited
2011
Mutations at tyrosine 641 (Y641F, Y641N, Y641S and Y641H) in the SET domain of EZH2 have been identified in patients with certain… Expand
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Highly Cited
2010
Highly Cited
2010
EZH2, the catalytic subunit of the PRC2 complex, catalyzes the mono- through trimethylation of lysine 27 on histone H3 (H3K27… Expand
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Highly Cited
2008
Highly Cited
2008
An intricate interplay between DNA methylation and polycomb-mediated gene silencing has been highlighted recently. Here we… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT Complex patterns of histone lysine methylation encode distinct functions within chromatin. We previously reported that… Expand
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Highly Cited
2006
Highly Cited
2006
Human enhancer of zeste 2 (EZH2) protein belongs to the multiprotein polycomb repressive complex 2, which also includes… Expand
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