Skip to search formSkip to main contentSkip to account menu

negative regulation of hemopoiesis

Known as: downregulation of hematopoiesis, down regulation of haemopoiesis, down-regulation of hemopoiesis 
Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. [GO_REF:0000058, GOC:pad, GOC:PARL, GOC:TermGenie, PMID… 
National Institutes of Health

Related topics

Related topics

2 relations
Hematopoiesis

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Sequentially inducible mouse models reveal that Npm1 mutation causes malignant transformation of Dnmt3a-mutant clonal hematopoiesis
Clonal hematopoiesis (CH) is a common aging-associated condition with increased risk of hematologic malignancy. Knowledge of the… 
Review
2019
Review
2019
Environmental Influences on Clonal Hematopoiesis.
Highly Cited
2016
Highly Cited
2016
Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt‐Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity
Adult‐repopulating hematopoietic stem cells (HSCs) emerge in low numbers in the midgestation mouse embryo from a subset of… 
2014
2014
Molecular basis of crosstalk between oncogenic Ras and the master regulator of hematopoiesis GATA‐2
Disease mutations provide unique opportunities to decipher protein and cell function. Mutations in the master regulator of… 
Highly Cited
2008
Highly Cited
2008
Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis.
Members of the tristetraprolin family of tandem CCCH finger proteins can bind to AU-rich elements in the 3'-untranslated region… 
2008
2008
Adenovirus-delivered CIAPIN1 small interfering RNA inhibits HCC growth in vitro and in vivo
Hepatocellular carcinoma (HCC) is an aggressive cancer with a poor prognosis. The specific cellular gene alterations responsible… 
Highly Cited
2006
Highly Cited
2006
AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis.
The Notch1-RBP-Jkappa and the transcription factor Runx1 pathways have been independently shown to be indispensable for the… 
Highly Cited
2004
Highly Cited
2004
A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development.
Notch1 is known to play a critical role in regulating fates in numerous cell types, including those of the hematopoietic lineage… 
Highly Cited
2004
Highly Cited
2004
Identification of a Cytokine-induced Antiapoptotic Molecule Anamorsin Essential for Definitive Hematopoiesis
Many growth factors and cytokines prevent apoptosis. Using an expression cloning method, we identified a novel antiapoptotic… 
Highly Cited
2001
Highly Cited
2001
Dimerization with PEBP2β protects RUNX1/AML1 from ubiquitin–proteasome‐mediated degradation
The RUNX family genes are the mammalian homologs of the Drosophila genes runt and lozenge, and members of this family function as… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)