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negative regulation of ERK5 cascade

Known as: down regulation of BMK cascade, negative regulation of BMK1 cascade, negative regulation of BMK signalling pathway 
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade. [GOC:add, ISBN… 
National Institutes of Health

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2 relations
ERK5 cascade

Broader (1)

biological control

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
BmK NT1-induced neurotoxicity is mediated by PKC/CaMKⅡ-dependent ERK1/2 and p38 activation in primary cultured cerebellar granule cells.
2017
2017
Enhancement of recombinant BmK AngM1 production in Pichia pastoris by regulating gene dosage, co-expressing with chaperones and fermenting in fed-batch mode
Abstract The scorpion peptide BmK AngM1 was reported to exhibit evident analgesic effect, but its yield by extraction from… 
2014
2014
Purification, characterization, and bioactivity of a new analgesic-antitumor peptide from Chinese scorpion Buthus martensii Karsch
2011
2011
Purification, characterization and functional expression of a new peptide with an analgesic effect from Chinese scorpion Buthus martensii Karsch (BmK AGP-SYPU1).
In this study, a new peptide named BmK AGP-SYPU1 with an analgesic effect was purified from the venom of Chinese scorpion Buthus… 
2008
2008
Anticonvulsant effect of BmK IT2, a sodium channel‐specific neurotoxin, in rat models of epilepsy
Background and purpose: The sodium channel is a primary target for treating central nervous system disorders such as epilepsy. In… 
2007
2007
Suppression by intrathecal BmK IT2 on rat spontaneous pain behaviors and spinal c-Fos expression induced by formalin
2006
2006
Chinese-scorpion (Buthus martensi Karsch) toxin BmK alphaIV, a novel modulator of sodium channels: from genomic organization to functional analysis.
In the present study, BmK alphaIV, a novel modulator of sodium channels, was cloned from venomous glands of the Chinese scorpion… 
2003
2003
Suppressive effects of BmK IT2 on nociceptive behavior and c‐Fos expression in spinal cord induced by formalin
In this study, the suppressive effects of BmK IT2, a kind of Na+ channel‐specific modulator from the venom of the scorpion Buthus… 
2001
2001
A new insect neurotoxin AngP1 with analgesic effect from the scorpion Buthus martensii Karsch: purification and characterization.
An insect toxin named BmK AngP1 was purified from the venom of the scorpion Buthus martensii Karsch (BmK). It also shows an… 
Highly Cited
1999
Highly Cited
1999
Covalent structures of BmK AS and BmK AS-1, two novel bioactive polypeptides purified from Chinese scorpion Buthus martensi Karsch.
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