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GABAergic neurons containing CCK‐8‐like and/or VIP‐like immunoreactivities in the rat hippocampus and dentate gyrus
The coexistence of cholecystokinin‐octapeptide‐like (CCK‐L) and/or vasoactive‐intestinal‐polypeptide‐like immunoreactive (VIP‐LI) materials and glutamate decarboxylase (GAD) was studied in the ratExpand
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人間感覚の客観的な評価方法は,ストレス低減 や快適性向上効果を持った商品や技術の開発に必 要であり, 微弱なストレスの評価が可能な高感度 指標が求められている。交感神経系は, ストレス に対して鋭敏に反応する。そこで, 交感神経活動 と関連した唾液中の物質を探索した。クロモグラ ニンA (CgA) は,副腎髄質クロム親和性細胞や交 感神経ニューロンから分泌される主要なタンパクExpand
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Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27
Vasoactive intestinal polypeptide (VIP), a 28-amino acid peptide originally isolated from porcine duodenum1, is present not only in gastrointestinal tissues but also in neural tissues, possibly as aExpand
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Evidence for different pre- and post-junctional receptors for neuropeptide Y and related peptides
The effects of neuropeptide Y (NPY), peptide YY (PYY), desamido-NPY and five C-terminal fragments of NPY or PYY were tested on different smooth muscle preparations in vitro. The fragments were NPYExpand
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Characterization of a high-affinity galanin receptor in the rat anterior pituitary: absence of biological effect and reduced membrane binding of the antagonist M15 differentiate it from the brain/gut
Structure-activity studies demonstrate that galanin fragments 1-15 and 2-29 are fully active, whereas fragment 3-29 has been reported to be inactive, in a number of different in vivo models. M15, aExpand
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The effect of the mammalian neuropeptide, gastrin-releasing peptide (GRP), on gastrointestinal and pancreatic hormone secretion in man.
Gastrin-releasing peptide, a newly isolated mammalian peptide similar in its structure and actions to the amphibian peptide, bombesin, has recently been localized to nerves in the brain, gut andExpand
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Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell
We have obtained evidence by autoradiography and immunocytochemistry that mature secretory granules of the pancreatic B-cell gain access to a lysosomal compartment (multigranular or crinophagicExpand
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Presence and coexistence of chromogranin A and multiple neuropeptides in Merkel cells of mammalian oral mucosa
By the use of light microscopic (LM) immunohistochemistry, Merkel cells of the mammalian oral mucosa have been examined for the presence and coexistence of some neuropeptides and of theExpand
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Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension.
Background Hypertension is a complex trait with an ill-defined genetic predisposition, in which adrenergic mechanisms seem to be involved even at the early stages. Chromogranin A is a pro-hormoneExpand
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Two neurotoxins (BmK I and BmK II) from the venom of the scorpion Buthus martensi Karsch: purification, amino acid sequences and assessment of specific activity.
Two neurotoxins, BmK I and BmK II, were purified from the venom of the Chinese scorpion Buthus martensi Karsch. The complete amino acid sequences of both toxins, each containing 64 amino acidExpand
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