neferine

 
National Institutes of Health

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Benzylisoquinolines

Papers overview

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2014
2014
Doxorubicin induced apoptosis was potentiated by neferine in human lung adenocarcima, A549 cells.
Doxorubicin (DOX) is the best anticancer agent that has ever been used, but acquired tumor resistance and dose limiting toxicity… (More)
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2014
2014
Neferine prevented hyperglycemia-induced endothelial cell apoptosis through suppressing ROS/Akt/NF-κB signal
Diabetes mellitus has been identified as a major risk factor for cardiovascular diseases. High glucose-induced endothelial… (More)
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2013
2013
Neferine induces reactive oxygen species mediated intrinsic pathway of apoptosis in HepG2 cells.
Evidence has accumulated concerning the medicinal application of Nelumbo nucifera in the treatment of various diseases. Neferine… (More)
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2012
2012
Protective Effect of Neferine Against Isoproterenol-Induced Cardiac Toxicity
The present study was designed to investigate the cardioprotective effect of neferine against isoproterenol-induced myocardial… (More)
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2011
2011
Effect of neferine on liver ischemia-reperfusion injury in rats.
INTRODUCTION Liver ischemia/reperfusion leads to the formation of reactive oxygen species (ROS) that cause liver injury, a… (More)
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2011
2011
Neferine inhibits cultured hepatic stellate cell activation and facilitates apoptosis: A possible molecular mechanism.
Neferine is a major alkaloid component of "Lian Zi Xin", embryos of the seeds of Nelumbo nucifera Gaertner, Nymphaeaceae… (More)
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2010
2010
Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis.
In this study, we evaluated the potential anti-fibrotic property of neferine, a bisbenzylisoquinline alkaloid extracted from the… (More)
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2004
2004
Multidrug resistance reversal in human gastric carcinoma cells by neferine.
AIM To investigate the reversal effect of neferine on multidrug resistance in human gastric carcinoma cell line. METHODS Cells… (More)
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1997
1997
[Effects of neferine on platelet aggregation in rabbits].
Neferine (Nef), a hypotensive agent with antiarrythmic action, is a dibenzyl isoquinoline alkaloid isolated from a Chinese… (More)
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1990
1990
[Effects of neferine on heart electromechanical activity in anaesthetized cats].
Neferine, an alkaloid extracted from the green seed embryo of Nelumbo nucifera Gaertn, has been shown to have anti-arrhythmic… (More)
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