necdin

Known as: Necdin Homolog (Mouse), Necdin (Mouse) Homolog, Prader-Willi Syndrome Chromosome Region 
Necdin (321 aa, ~36 kDa) is encoded by the human NDN gene. This protein plays a role in suppression of cell growth in postmitotic neurons.
National Institutes of Health

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Topic mentions per year

1991-2017
051019912017

Papers overview

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2009
2009
Hematopoietic stem cell (HSC) proliferation is tightly regulated by a poorly understood complex of positive and negative cell… (More)
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Highly Cited
2008
Highly Cited
2008
Sirtuin1 (Sirt1), a mammalian homolog of yeast Sir2, deacetylates the tumor suppressor protein p53 and attenuates p53-mediated… (More)
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Highly Cited
2006
Highly Cited
2006
Necdin, a member of the MAGE (melanoma antigen) protein family, is expressed predominantly in terminally differentiated neurons… (More)
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Highly Cited
2005
Highly Cited
2005
The insulin/IGF-1 (insulin-like growth factor 1) signalling pathway promotes adipocyte differentiation via complex signalling… (More)
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Highly Cited
2000
Highly Cited
2000
Prader-Willi syndrome (PWS) is a complex neurogenetic disorder with considerable clinical variability that is thought in large… (More)
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2000
2000
Necdin is a 325-amino-acid residue protein encoded by a cDNA clone isolated from neurally differentiated embryonal carcinoma… (More)
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Highly Cited
1999
Highly Cited
1999
Necdin is expressed in virtually all postmitotic neurons, and ectopic expression of this protein suppresses cell proliferation… (More)
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Highly Cited
1998
Highly Cited
1998
Necdin is a nuclear protein expressed in virtually all postmitotic neurons, and ectopic expression of this protein strongly… (More)
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Highly Cited
1997
Highly Cited
1997
Human chromosome 15q11-q13 contains genes that are imprinted and expressed from only one parental allele. Prader-Willi syndrome… (More)
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Highly Cited
1997
Highly Cited
1997
Prader-Willi syndrome (PWS) is a neurogenetic disorder that results from the absence of a normal paternal contribution to the… (More)
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