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naloxone-3-glucuronide

 
National Institutes of Health

Papers overview

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2019
2019
BACKGROUND Naloxone, an opioid receptor antagonist, is used as a pharmacological tool to detect tonic endogenous activation of… Expand
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2013
2013
A hydrophilic interaction chromatography-tandem mass spectrometric (HILIC-MS/MS) method was developed for the direct… Expand
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2008
2008
BACKGROUND There is an increasing body of evidence supporting the need for prophylactic management of the adverse events (AEs… Expand
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2008
2008
Background  Constipation is a significant side effect of opioid therapy. We have previously demonstrated that naloxone‐3… Expand
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Highly Cited
2007
Highly Cited
2007
A method using liquid chromatography-electrospray ionization-tandem mass spectrometry was developed and validated for the… Expand
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2006
2006
The effect of the opioid antagonists naloxone-3-glucuronide and N-methylnaloxone on rat colon motility after morphine stimulation… Expand
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1989
1989
Metabolic interaction between naloxone and morphine has been studied in vitro in human liver microsomes. Morphine and naloxone… Expand
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Highly Cited
1988
Highly Cited
1988
The glucuronidation of morphine and naloxone was investigated in several regions of the human brain. Post-mortem brain tissue… Expand
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1976
1976
A sensitive method is described for the estimation of [14C]naloxone in biological materials. After a 1 mg/kg s.c. dose of [14C… Expand
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1970
1970
  • J. Fujimoto
  • Proceedings of the Society for Experimental…
  • 1970
  • Corpus ID: 45110265
Summary Using column chromatography with Amberlite XAD-2 and silica gel and countercurrent analysis, a metabolite of naloxone was… Expand
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