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Naloxone

Known as: Naloxona, L-Naloxone, (-)-Naloxone 
A thebaine derivate with competitive opioid antagonistic properties. Naloxone reverses the effects of opioid analgesics by binding to the opioid… 
National Institutes of Health

Related topics

Related topics

40 relations
0.4 ML Naloxone Hydrochloride 1 MG/ML Auto-Injector [Evzio]Buprenorphine / NaloxoneBuprenorphine 2 MG / Naloxone 0.5 MG Sublingual TabletBuprenorphine 2.1 MG / Naloxone 0.3 MG Buccal Film

Narrower (19)

14-hydroxydihydromorphazineBunavailEvzioMRZ-2593

Broader (2)

Heterocyclic Compounds, Bridged-RingNarcotic Antagonists

Papers overview

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Highly Cited
1985
Highly Cited
1985
Naloxone potentiates the cardiovascular effects of catecholamines in canine hemorrhagic shock.
Endogenous opioids are released during stress and appear to contribute to the cardiovascular suppression seen in shock. When the… 
1985
1985
Naloxone-induced secretion of LH in the male Syrian hamster: modulation by photoperiod and gonadal steroids.
The role of endogenous opiates in the regulation of photoperiodically induced testicular regression was studied in the male… 
1985
1985
Intracoronary naloxone in hemorrhagic shock: dose-dependent stereospecific effects.
Treatment with naloxone improves cardiovascular function and survival in a variety of shock models, and numerous sites and… 
1984
1984
Effects of naloxone and electroacupuncture treatment on plasma concentrations of LH in sheep.
Mature ewes were injected intravenously with the opioid antagonist naloxone (1.1 mg/kg) during the breeding season. Ewes with… 
1984
1984
Pain Measurement and Pain Modification by Naloxone in Patients with Asymptomatic Myocardial Ischemia
Although it has been known for some time that myocardial infarction can occur silently, an increasing number of reports now… 
Highly Cited
1982
Highly Cited
1982
Antagonist of gonadotropin-releasing hormone blocks naloxone-induced elevations in serum luteinizing hormone.
Administration of a gonadotropin-releasing hormone (GnRH) antagonist, [D-Phe, D-Trp3.6]-GnRH, to immature female rats blocks the… 
1982
1982
Effect of naloxone on pituitary hypersecretory syndromes.
Naloxone administration acutely lowered elevated plasma ACTH concentrations present in subjects with Nelson's syndrome or primary… 
1981
1981
Morphine and naloxone: effects on beta-endorphin immunoreactivity in canine plasma and secretions from rat pituitaries.
Morphine and naloxone were administered to five dogs to assess their effects on endogenous opioid release. Morphine (3 mg/20 kg… 
Highly Cited
1978
Highly Cited
1978
The relationship between enkephalin degradation and opiate receptor occupancy.
Enkephalin, a brain peptide with morphine-like activities, is rapidly inactivated by a membrane-associated aminopeptidase present… 
1973
1973
Treatment of propoxyphene overdosage with naloxone.
Reported are two patients, one child and one adult, with propoxyphene-induced coma successfully reversed with naloxone. We…