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Naloxone
Known as:
Naloxona
, L-Naloxone
, (-)-Naloxone
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A thebaine derivate with competitive opioid antagonistic properties. Naloxone reverses the effects of opioid analgesics by binding to the opioid…
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National Institutes of Health
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Related topics
Related topics
40 relations
0.4 ML Naloxone Hydrochloride 1 MG/ML Auto-Injector [Evzio]
Buprenorphine / Naloxone
Buprenorphine 2 MG / Naloxone 0.5 MG Sublingual Tablet
Buprenorphine 2.1 MG / Naloxone 0.3 MG Buccal Film
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Narrower (19)
14-hydroxydihydromorphazine
Bunavail
Evzio
MRZ-2593
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Broader (2)
Heterocyclic Compounds, Bridged-Ring
Narcotic Antagonists
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis
A. Walley
,
A. Walley
,
+7 authors
A. Ozonoff
British medical journal
2013
Corpus ID: 2411937
Objective To evaluate the impact of state supported overdose education and nasal naloxone distribution (OEND) programs on rates…
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Highly Cited
2003
Highly Cited
2003
Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone.
P. Fudala
,
T. Bridge
,
+13 authors
D. Tusel
New England Journal of Medicine
2003
Corpus ID: 41629435
BACKGROUND Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone has been…
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Highly Cited
1991
Highly Cited
1991
A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study.
M. Bracken
,
M. Shepard
,
+14 authors
H. Winn
New England Journal of Medicine
1991
Corpus ID: 44393370
Studies in animals indicate that methylprednisolone and naloxone are both potentially beneficial in acute spinal-cord injury, but…
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Highly Cited
1980
Highly Cited
1980
Intrathecal morphine in mice: a new technique.
J. L. Hylden
,
G. Wilcox
European Journal of Pharmacology
1980
Corpus ID: 40838880
Highly Cited
1977
Highly Cited
1977
Pain relief by electrical stimulation of the central gray matter in humans and its reversal by naloxone.
Y. Hosobuchi
,
J. Adams
,
R. Linchitz
Science
1977
Corpus ID: 23076543
Relief of intractable pain was produced in six human patients by stimulation of electrodes permanently implanted in the…
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Highly Cited
1977
Highly Cited
1977
Endogenous opioid peptides: multiple agonists and receptors
J. Lord
,
A. Waterfield
,
J. Hughes
,
H. Kosterlitz
Nature
1977
Corpus ID: 4160761
Opioid peptides were assayed by inhibition of 3H-naloxone and 3H-leu-enkephalin binding in brain homogenates and by depression of…
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Highly Cited
1976
Highly Cited
1976
Chronic catheterization of the spinal subarachnoid space
T. Yaksh
,
T. Rudy
Physiology and Behavior
1976
Corpus ID: 8199668
Highly Cited
1976
Highly Cited
1976
Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist
H. Akil
,
D. Mayer
,
J. Liebeskind
1976
Corpus ID: 72157853
Analgesia produced by focal electrical stimulation of the brain is partially reversed by the narcotic antagonist naloxone. The…
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Highly Cited
1975
Highly Cited
1975
Isolation of an endogenous compound from the brain with pharmacological properties similar to morphine
J. Hughes
Brain Research
1975
Corpus ID: 42397265
Highly Cited
1973
Highly Cited
1973
Opiate Receptor: Demonstration in Nervous Tissue
C. Pert
,
S. Snyder
Science
1973
Corpus ID: 21783674
Tritiated naloxone, a powerful opiate antagonist, specifically binds to an opiate receptor of mammalian brain and guinea pig…
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