Naloxone

Known as: Naloxona, L-Naloxone, (-)-Naloxone 
A thebaine derivate with competitive opioid antagonistic properties. Naloxone reverses the effects of opioid analgesics by binding to the opioid… (More)

Topic mentions per year

Topic mentions per year

1952-2017
050019522016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
BACKGROUND Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone has been… (More)
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Highly Cited
2000
Highly Cited
2000
Degeneration of dopaminergicrgic neurons in the substantia nigra of the brain is a hallmark of Parkinson's disease and… (More)
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Highly Cited
1999
Highly Cited
1999
We investigated the mechanisms underlying the activation of endogenous opioids in placebo analgesia by using the model of human… (More)
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Highly Cited
1997
Highly Cited
1997
The effects of the active ingredient of Cannabis, Delta9-tetrahydrocannabinol (Delta9-THC), and of the highly addictive drug… (More)
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Highly Cited
1992
Highly Cited
1992
The 1-year follow-up data of a multicenter randomized controlled trial of methylprednisolone (30 mg/kg bolus and 5.4 mg/kg/hr for… (More)
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Highly Cited
1990
Highly Cited
1990
Studies in animals indicate that methylprednisolone and naloxone are both potentially beneficial in acute spinal-cord injury, but… (More)
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Highly Cited
1980
Highly Cited
1980
A simple, rapid technique for intrathecal injections by lumbar puncture in unanesthetized mice is described. Intrathecal [3H… (More)
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Highly Cited
1979
Highly Cited
1979
The freezing behavior of the rat that occurs following painful electric shock was found to increase when the animal was… (More)
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Highly Cited
1977
Highly Cited
1977
Relief of intractable pain was produced in six human patients by stimulation of electrodes permanently implanted in the… (More)
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Highly Cited
1976
Highly Cited
1976
To administer drugs into the spinal subarachnoid space of unanesthetized and intact rats and rabbits, a procedure is described… (More)
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