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nafamostat mesilate
Known as:
Nafamostat Dimethanesulfonate
, Nafamostat Mesylate
, 6-Amidino2-naphthyl 4-guanidinobenzoate
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National Institutes of Health
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Related topics
Related topics
2 relations
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FUT 175
nafamostat
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
The Results of Severe Acute Pancreatitis Treatment With Continuous Regional Arterial Infusion of Protease Inhibitor and Antibiotic: A Randomized Controlled Study
Marta Piaścik
,
G. Rydzewska
,
+4 authors
A. Gabryelewicz
Pancreas
2010
Corpus ID: 23729179
Objectives: A randomized controlled trial was conducted to clarify whether continuous regional arterial infusion (CRAI) of…
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2010
2010
Inhibition of intraluminal pancreatic enzymes with nafamostat mesilate improves clinical outcomes after hemorrhagic shock in swine.
Hubert D Kim
,
D. Malinoski
,
+7 authors
D. Hoyt
Journal of Trauma
2010
Corpus ID: 11732470
BACKGROUND Recent studies suggest that intraluminal pancreatic enzymes play a major role in the initiation of the inflammatory…
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2009
2009
Combination chemotherapy of nafamostat mesilate with gemcitabine for pancreatic cancer targeting NF-kappaB activation.
T. Uwagawa
,
P. Chiao
,
T. Gocho
,
Shouichi Hirohara
,
T. Misawa
,
K. Yanaga
Anticancer Research
2009
Corpus ID: 22926410
PURPOSE Gemcitabine is currently the standard first-line chemotherapeutic agent for pancreatic cancer. However, chemoresistance…
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2009
2009
A phase I study of full-dose gemcitabine and regional arterial infusion of nafamostat mesilate for advanced pancreatic cancer.
T. Uwagawa
,
T. Misawa
,
+7 authors
K. Yanaga
Annals of Oncology
2009
Corpus ID: 3994447
BACKGROUND The primary end points of this study were to determine the dose-limiting toxic effects (DLTs), maximum tolerated dose…
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2004
2004
Transporter-mediated renal handling of nafamostat mesilate.
Qing Li
,
Y. Sai
,
Y. Kato
,
H. Muraoka
,
I. Tamai
,
A. Tsuji
Journal of Pharmacy and Science
2004
Corpus ID: 37217442
Nafamostat mesilate (NM) is a serine-protease inhibitor that is rapidly eliminated from the circulation and accumulated in the…
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2003
2003
A potent tryptase inhibitor nafamostat mesilate dramatically suppressed pulmonary dysfunction induced in rats by a radiographic contrast medium
T. Sendo
,
Y. Itoh
,
+5 authors
R. Oishi
British Journal of Pharmacology
2003
Corpus ID: 44878525
Intravenous injection of ioxaglate (4 g iodine kg−1), an iodinated radiographic contrast medium, caused a marked protein…
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1995
1995
Hyperkalemia due to nafamostat mesylate.
H. Kitagawa
,
H. Chang
,
T. Fujita
New England Journal of Medicine
1995
Corpus ID: 39997780
To the Editor: Nafamostat mesylate (6-amidino-2-naphthyl p-guanidinobenzoate, dimethanesulfonate; molecular weight, 540) is a…
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1994
1994
Mechanisms of the hyperkalaemia caused by nafamostat mesilate: effects of its two metabolites on Na+ and K+ transport properties in the rabbit cortical collecting duct
S. Muto
,
M. Imai
,
Y. Asano
British Journal of Pharmacology
1994
Corpus ID: 19089745
1 The present experiments were undertaken to determine the mechanism(s) of hyperkalaemia caused by nafamostat mesilate (NM), a…
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1993
1993
Effect of nafamostat mesilate on Na+ and K+ transport properties in the rabbit cortical collecting duct
S. Muto
,
M. Imai
,
Y. Asano
British Journal of Pharmacology
1993
Corpus ID: 36889097
1 To determine the mechanism(s) of hyperkalemia caused by nafamostat mesilate (NM), a serine‐protease inhibitor, we investigated…
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1989
1989
The effects of nafamostat mesilate (FUT-175) on caerulein-induced acute pancreatitis in the rat
J. Wisner
,
S. Ozawa
,
I. Renner
International Journal of Pancreatology
1989
Corpus ID: 39313155
SummaryWe examined the ability of a highly potent synthetic protease inhibitor, nafamostat mesilate (FUT-175), to protect the rat…
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