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Neither the route of electron transport nor the sites or mechanism of superoxide production in mitochondrial complex I has been… Expand Wetested whether mitochondria function as the O 2 sensorunderlying hypoxic pulmonary vasoconstriction (HPV). In buffer-perfused… Expand Reactive oxygen species (ROS) have been proposed to participate in the induction of cardiac preconditioning. However, their… Expand Formation of H2O2 has been studied in rat heart mitochondria, pretreated with H2O2 and aminotriazole to lower their antioxidant… Expand On the basis of x-ray diffraction data to a resolution of 2.9 angstroms, atomic models of most protein components of the bovine… Expand We have examined the substrate specificity and inhibitor sensitivity of H2O2 formation by rat heart mitochondria. Active H2O2… Expand The effect of specific irreversible inhibitors of complexes I, III, IV and V of the mitochondrial respiratory chain, (rotenone… Expand Much evidence indicates that superoxide is generated from O2 in a cyanide-sensitive reaction involving a reduced component of… Expand The inhibitory action and binding characteristics of the new anti-fungal antibiotic myxothiazol has been described in [ 1,2… Expand Myxothiazol inhibited oxygen consumption of beef heart mitochondria in the presence and absence of 2,4-dinitrophenol, as well as… Expand