mycothiol-dependent detoxification

The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2016
01220002016

Papers overview

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2016
2016
The immediate post-condensation steps in lincomycin biosynthesis are reminiscent of the mycothiol-dependent detoxification system… (More)
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2008
2008
Mycothiol (MSH) is the major thiol in Actinobacteria and plays a role analogous to that of glutathione. The biosynthetic pathway… (More)
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2008
2008
Marine actinomycetes have generated much recent interest as a potentially valuable source of novel antibiotics. Like terrestrial… (More)
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2007
2007
Synthesis and evaluation of a chemical library of inhibitors of the mycothiol biosynthesis enzyme GlcNAc-Ins deacetylase (MshB… (More)
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2004
2004
Mycothiol (MSH), a functional analogue of glutathione (GSH) that is found exclusively in actinomycetes, reacts with electrophiles… (More)
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2004
2004
Mycothiol (MSH) is the major cellular thiol in Mycobacterium tuberculosis (M.tb). We hypothesize that the mycothiol-dependent… (More)
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2003
2003
Mycothiol is an abundant small molecular weight thiol found only in actinomycetes, which include mycobacteria. Mycothiol… (More)
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2000
2000
Mycothiol, 1-D-myo-inosityl-2-(N-acetylcysteinyl)amido-2-deoxy-alpha-D-glucopyranoside (MSH), is composed of N-acetylcysteine… (More)
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2000
2000
Mycothiol is a novel thiol produced only by actinomycetes and is the major low-molecular-weight thiol in mycobacteria. Mycothiol… (More)
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