mutilin
National Institutes of Health
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14-O-[(4,6-Diaminopyrimidine-2-yl)thioacetyl] mutilin (DPTM), a novel pleuromutilin candidate with a substituted pyrimidine…
Recently, function-preserving operations have becoTne popular, and pylorus preserving pancreatoduodenectomy {PPPD) is freqLiently…
The invention discloses a preparation method for synthesizing intermediate mutilin from pleuromutilin antibiotics, which…
The emergence of multi-drug-resistant microorganisms leads to a concerted search for leading compounds with particular…
(57) Abstract: useful in the treatment of bacterial infections formula (IA): (In the formula, R
FIELD: chemistry. SUBSTANCE: product: mutilin derivatives. Reagent 1: aminomutilin. Reagent 2: D-valine which is protected…
Derivatives of pleuromutilin, formed during the fermentation of pleuromutilin, were isolated and their structure determined. 14…
A number of derivatives of pleuromutilin (I) and of its degradation product, mutilin (II1, was prepared. The new monotosylation…