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monoclonal antibody 3F8

Known as: 3F8 Monoclonal Antibody, 3f8, MOAB 3F8 
A murine monoclonal antibody directed against the cell-surface, tumor-associated antigen ganglioside GD2. Vaccination with monoclonal antibody 3F8… Expand
National Institutes of Health

Papers overview

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2018
2018
ABSTRACT Natural killer (NK) cell-mediated antibody-dependent toxicity is a potent mechanism of action of the anti-GD2 murine… Expand
2011
2011
PURPOSE Pain can hinder immunotherapy with anti-G(D2) monoclonal antibodies (MoAbs) like 3F8. Heat-modified 3F8 (HM3F8) lacks… Expand
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2005
2005
The present study evaluated the ability of the anti-GD2 ganglioside monoclonal antibody 3F8 to target tumor sites in patients… Expand
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Highly Cited
2002
Highly Cited
2002
  • N. Cheung, S. Modak
  • Clinical cancer research : an official journal of…
  • 2002
  • Corpus ID: 10224190
PURPOSE In vitro beta-glucan can enhance tumor cytotoxicity through iC3b receptors on leukocytes. We tested if (1-->3),(1-->4… Expand
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Highly Cited
1998
Highly Cited
1998
3F8 is an IgG3 murine monoclonal antibody directed against the ganglioside GD2. In a phase II study, 3F8 was administered i.v. to… Expand
1993
1993
Disialoganglioside GD2 is widely expressed among neuroblas‐tomas, melanomas, small‐cell lung carcinoma, sarcomas and brain tumors… Expand
Highly Cited
1989
Highly Cited
1989
3F8 is a murine monoclonal IgG3 antibody specific for the tumor-associated antigen ganglioside GD2. Previous in vitro studies… Expand
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1989
1989
The monoclonal antibody 3F8 has been described as binding to the ganglioside GD2. This antibody, of the IgG3 isotype, has been… Expand
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Highly Cited
1987
Highly Cited
1987
The murine IgG3 monoclonal antibody (MoAb) 3F8, specific for the ganglioside GD2, activates human complement, is active in… Expand
Highly Cited
1987
Highly Cited
1987
3F8 is a murine IgG3 monoclonal antibody specific for the antigen disialoganglioside GD2. Immunofluorescence staining showed… Expand