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moexiprilat

Known as: 2-(2-(1-carboxy-3-phenylpropyl)amino-1-oxopropyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid 
A non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexiprilat competitively inhibits ACE, thereby… 
National Institutes of Health

Related topics

Related topics

3 relations
Moexiprilat Hydrochloride

Narrower (1)

RS 10029

Broader (1)

Tetrahydroisoquinolines

Papers overview

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2006
2006
Monitoring the metabolism of moexipril to moexiprilat using high-performance liquid chromatography-electrospray ionization mass spectrometry.
High-performance liquid chromatography combined with a UV absorbance detector and electrospray ionization mass spectrometer is… 
2003
2003
ACE Inhibition with Moexipril
ACE inhibitors induce metabolic changes and exert cardioprotective and vasoprotective properties, some of which cannot be… 
1997
1997
Effects of moexiprilat on oestrogen‐stimulated cardiac fibroblast growth
The effects of 2‐2‐(1‐(ethoxycarbonyl)‐3‐phenylpropyl)‐[amino‐oxopropyl]−6,7‐dimethoxy‐1,2,3,4‐tetrahydroisoquinoline‐3… 
1997
1997
Pharmacological and toxicological studies of the new angiotensin converting enzyme inhibitor moexipril hydrochloride.
The pharmacodynamic and toxicological profile of the new angiotensin converting enzyme (ACE) inhibitor moexipril (CAS 82586-52-5… 
1996
1996
Potentiation of the biological efficacy of bradykinin by ACE inhibitors: a shift in the affinity of the B2 receptor?
1996
1996
Moexipril versus captopril in patients with mild to moderate hypertension.
Moexipril is a new, long-acting angiotensin-converting enzyme (ACE) inhibitor. In contrast to captopril, it is a prodrug of the… 
1995
1995
Tricenter Assessment of the Efficacy of the ACE Inhibitor, Moexipril, by Ambulatory Blood Pressure Monitoring
To assess the efficacy and time‐dependent effects of once‐daily moexipril, a nonsulfhydryl ester prodrug of the angiotensin… 
1995
1995
Simultaneous determination of moexipril and moexiprilat, its active metabolite, in human plasma by gas chromatography-negative-ion chemical ionization mass spectrometry.
1993
1993
Relaxation of isolated coronary arteries by angiotensin-converting enzyme inhibitors: role of endothelium-derived kinins.
In the presence of indomethacin (10 microM) and without previous exposure to bradykinin, two angiotensin-converting enzyme (ACE… 
1992
1992
Role of Endothelium‐Derived Bradykinin in the Control of Vascular Tone
We have investigated the effects of angiotensin-converting enzyme (ACE) inhibitors on intracellular Ca2+ levels in human cultured… 
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