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mitogen-activated protein kinase 7

Known as: Mitogen-Activated Protein Kinase 7 [Chemical/Ingredient], Kinase, BMK1, ERK5 Kinase 
A 110-kDa extracellular signal-regulated MAP kinase that is activated in response to cellular stress and by GROWTH FACTOR RECEPTORS-mediated pathways… 
National Institutes of Health

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In BloodMAPK7 geneProcess of secretionantagonists & inhibitors

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MAPK7 protein, human

Papers overview

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2020
2020
MicroRNA-187 suppresses the proliferation migration and invasion of human osteosarcoma cells by targeting MAPK7.
PURPOSE Osteosarcoma is one of the rare but fatal malignancies. The high metastatic rate, late diagnosis, emergence of drug… 
2016
2016
MiR-143 suppresses the epithelial-mesenchymal transition of spinal glioblastoma through down-regulation of ERK5.
The spinal glioblastoma (GBM) represents the one of most common tumors in humans. However, the biological processes and molecular… 
2016
2016
Platelet CD36 Potentiates Thrombus Formation in Hyperlipidemic Conditions By Activating Redox Sensitive MAP Kinase ERK5
Atherosclerotic plaque instability is a pathological process that can lead to ischemic emergencies, such as myocardial infarction… 
2015
2015
Abstract 38: ERK5 inhibitor XMD8-92 for malignant mesothelioma treatment: A preclinical study
Malignant mesothelioma (MM) is an aggressive cancer in dire need of successful treatment. We are first to demonstrate that… 
2013
2013
Overexpression of MEKK2 is associated with colorectal carcinogenesis
Mitogen-activated protein kinase kinase kinase 2 (MEKK2) is an important upstream mediator of the extracellular signal-regulated… 
2013
2013
, Anita Alexa and ( ERK 5 ) Module Extracellular Signal Regulated Kinase 5 Assembly and Activation of the Structural Mechanism for the Specific
2010
2010
ERK5 Contributes to VEGF Alteration in Diabetic Retinopathy
Diabetic retinopathy is one of the most common causes of blindness in North America. Several signaling mechanisms are activated… 
2007
2007
Big Mitogen-Activated Protein Kinase: A New Player in Vascular Remodeling
Big mitogen-activated protein kinase (BMK1), also termed extracellular signal regulated kinase 5 (ERK5), is the most recently… 
2003
2003
Activation of gp 130 Transduces Hypertrophic Signal Through Interaction of Scaffolding / Docking Protein Gab 1 With Tyrosine Phosphatase SHP 2 in Cardiomyocytes
Grb2-associated binder-1 (Gab1) is a scaffolding/docking protein and contains a Pleckstrin homology domain and potential binding… 
2003
2003
Scaffolding / Docking Protein Gab 1 With Tyrosine Phosphatase SHP 2 in Cardiomyocytes Activation of gp 130 Transduces Hypertrophic Signal Through Interaction of
Grb2-associated binder-1 (Gab1) is a scaffolding/docking protein and contains a Pleckstrin homology domain and potential binding… 
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