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MAPK7 gene

Known as: MAPK7, extracellular-signal-regulated kinase 5, BMK1 
This gene is involved in the control of cell proliferation and transcriptional regulation.
National Institutes of Health

Related topics

Related topics

10 relations
Cell Cycle ControlCell ProliferationMAPK4 geneMAPK7 protein, human

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MAPK7 wt Allele

Papers overview

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2020
2020
MAPK7 variants related to prognosis and chemotherapy response in osteosarcoma.
2020
2020
[Effects of WNK1 on Human Chronic Myeloid Leukemia K562 Cells via MAPK7 Phosphorylation and Its Relative Mechanism].
OBJECTIVE To investigate the biological effects and mechanism of WNK1 on K562 cells through regulating MAPK7. METHODS Cells… 
2017
2017
ATM/MAPK7 crosstalk in cancer
Cells have evoked mechanisms, globally named the DNA damage response (DDR), to detect, signals and repair DNA lesions, which are… 
Highly Cited
2006
Highly Cited
2006
Expressed in the Yeast Saccharomyces cerevisiae, Human ERK5 Is a Client of the Hsp90 Chaperone That Complements Loss of the Slt2p (Mpk1p) Cell Integrity Stress-Activated Protein Kinase
ABSTRACT ERK5 is a mitogen-activated protein (MAP) kinase regulated in human cells by diverse mitogens and stresses but also… 
2006
2006
Global Gene Expression Analysis of ERK5 and ERK1/2 Signaling Reveals a Role for HIF-1 in ERK5-mediated Responses*
ERK5 is a recently characterized MAPK, which is most similar to the well studied ERK1/2 subfamily but uses distinct mechanisms to… 
Highly Cited
2005
Highly Cited
2005
BMK1/ERK5 Is a Novel Regulator of Angiogenesis by Destabilizing Hypoxia Inducible Factor 1&agr;
Big MAP kinase 1 (BMK1 or ERK5) is a key mediator of endothelial cell (EC) function as shown by impaired embryonic angiogenesis… 
2005
2005
Protein kinase C alpha, betaI, and betaII isozymes regulate cytokine production in mast cells through MEKK2/ERK5-dependent and -independent pathways.
Regulation of MAPK pathways by PKC isoforms was examined in murine bone marrow-derived mast cells (BMMCs). The PKCalpha, betaI… 
2004
2004
14-3-3β Binds to Big Mitogen-activated Protein Kinase 1 (BMK1/ERK5) and Regulates BMK1 Function*
Big mitogen-activated kinase 1 (BMK1/ERK5) is a member of the MAPK family activated by growth factors that mediates cell growth… 
2004
2004
14-3-3 Binds to Big Mitogen-activated Protein Kinase 1 ( BMK 1 / ERK 5 ) and Regulates BMK 1 Function *
Big mitogen-activated kinase 1 (BMK1/ERK5) is a member of the MAPK family activated by growth factors that mediates cell growth… 
1998
1998
Assignment1 of Big MAP Kinase (PRKM7) to human chromosome 17 band p11.2 with somatic cell hybrids
Big MAP kinase BMK1 (Lee et al., 1995), also referred to as ERK5 (extracellular signal regulated kinase 5; Zhou et al., 1995) or… 
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