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mitoclomine

Known as: N,N-bis(2-chloroethyl)- 4-methoxy-3-methyl-1-naphthylamine, N,N-bis(2-chloroethyl)4-amino-2-methyl-1-methoxy-naphthalene 
An aromatic nitrogen mustard derivative with potential antineoplastic activity. Mitoclomine alkylates DNA and appears to concentrate primarily in the… Expand
National Institutes of Health

Papers overview

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2007
2007
  • I. E. ADDTSON, J. XV. B. BABBAGEt, Fronm
  • 2007
  • Corpus ID: 157062857
-The effects of mitochlomine, an anti-tumour agent, and of cortisone acetate on the antibody response of mice to thymus-dependent… Expand
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1990
1990
Previous studies have shown that human leukaemic cells and certain tumour tissues have a higher receptor-mediated uptake of low… Expand
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1981
1981
The effects of mitoclomine, an anti-tumour agent, and of cortisone acetate on the antibody response of mice to thymus-dependent… Expand
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1980
1980
SummaryChlorambucil, phenyl acetic mustard, melphalan and mitoclomine are aromatic nitrogen mustard derivatives. These drugs show… Expand
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1979
1979
The effects of a variety of agents on the mouse antibody response to sheep red cells (SRC) and Escherichia coli… Expand
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1978
1978
1. The absorption, distribution and elimination of a new alkylating agent, N,N-bis(2'-chloroethyl)4-amino-2-methyl-1… Expand
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1975
1975
Phase I-II trial of mitoclomine in chronic lymphocytic leukemia (CLL) is described. Twenty seven courses of mitoclomine were… Expand
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1971
1971
The formula of Mitoclomine (W.B. 7007) was suggested by Granger in 1966 (1) as that of a useful cytotoxic agent, and confirmed in… Expand
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