Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 206,148,011 papers from all fields of science
Search
Sign In
Create Free Account
mitoclomine
Known as:
N,N-bis(2-chloroethyl)- 4-methoxy-3-methyl-1-naphthylamine
, N,N-bis(2-chloroethyl)4-amino-2-methyl-1-methoxy-naphthalene
An aromatic nitrogen mustard derivative with potential antineoplastic activity. Mitoclomine alkylates DNA and appears to concentrate primarily in the…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
2 relations
Narrower (1)
NSC-114575
Broader (1)
Nitrogen Mustard Compounds
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Br . J . exp . Path . ( 1981 ) 62 , 74 THYMUS-DEPENDENT AND THYMUS-INDEPENDENT ANTIBODY RESPONSES : CONTRASTING PATTERNS OF IMMUNOSUPPRESSION
I. E. Addtson
,
J. X. B. BABBAGEt
,
Fronm
2007
Corpus ID: 157062857
-The effects of mitochlomine, an anti-tumour agent, and of cortisone acetate on the antibody response of mice to thymus-dependent…
Expand
2004
2004
Comparative physico-chemical properties, biological effects, and disposition in mice of four nitrogen mustards
D. Godenèche
,
J. Madelmont
,
M. Moreau
,
R. Plagne
,
G. Meyniel
Cancer Chemotherapy and Pharmacology
2004
Corpus ID: 20570902
SummaryChlorambucil, phenyl acetic mustard, melphalan and mitoclomine are aromatic nitrogen mustard derivatives. These drugs show…
Expand
Highly Cited
1990
Highly Cited
1990
Low density lipoprotein for delivery of a water-insoluble alkylating agent to malignant cells. In vitro and in vivo studies of a drug-lipoprotein complex.
S. Vitols
,
K. Söderberg-Reid
,
M. Masquelier
,
B. Sjöström
,
C. Peterson
British Journal of Cancer
1990
Corpus ID: 567855
Previous studies have shown that human leukaemic cells and certain tumour tissues have a higher receptor-mediated uptake of low…
Expand
1981
1981
Thymus-dependent and thymus-independent antibody responses: contrasting patterns of immunosuppression.
I. Addison
,
J. Babbage
British journal of experimental pathology
1981
Corpus ID: 12361523
The effects of mitoclomine, an anti-tumour agent, and of cortisone acetate on the antibody response of mice to thymus-dependent…
Expand
1979
1979
Time-dependence and selectivity of immunosuppressive agents.
M. Berenbaum
Immunology
1979
Corpus ID: 32137526
The effects of a variety of agents on the mouse antibody response to sheep red cells (SRC) and Escherichia coli…
Expand
1979
1979
[Relationship of labeled molecules in the pharmacokinetic study of alkylating agents (chlorambucil, melphalan, mitoclomine) and glycosyl nitrosoureas (RFCNU and RPCNU)].
G. Meyniel
,
D. Godenech
Nouvelle revue francaise d'hematologie
1979
Corpus ID: 5761888
1979
1979
L'apport des molecules marquees dans l'etude pharmacocinetique d'agents alkylants (chlorambucil, melphalan, mitoclomine) et de glycosyl nitrosourees (RFCNU et RPCNU).
G. Meyniel
,
D. Godenech
1979
Corpus ID: 87827545
1978
1978
Disposition of a new alkylating agent [14C]mitoclomine (N,N-bis(2'-chloroethyl)4-amino-2-methyl-1-methoxy-naphthalene).
D. Godenèche
,
J. Madelmont
,
M. Moreau
,
R. Plagne
Xenobiotica; the fate of foreign compounds in…
1978
Corpus ID: 25713309
1. The absorption, distribution and elimination of a new alkylating agent, N,N-bis(2'-chloroethyl)4-amino-2-methyl-1…
Expand
1975
1975
Phase I-II clinical trial with mitoclomine (NSC-114575) in chronic lymphocytic leukemia.
E. Longeval
,
D. Ganglji
,
P. Stryckmans
,
Y. Kenis
Cancer chemotherapy reports
1975
Corpus ID: 8904897
Phase I-II trial of mitoclomine in chronic lymphocytic leukemia (CLL) is described. Twenty seven courses of mitoclomine were…
Expand
1971
1971
Investigations into the lymphopaenic and immunosuppressive properties of the antitumour agent, mitoclomine.
M. Fox
,
R. Rees
,
D. H. Bennett
,
L. Henry
Lymphology
1971
Corpus ID: 44866122
The formula of Mitoclomine (W.B. 7007) was suggested by Granger in 1966 (1) as that of a useful cytotoxic agent, and confirmed in…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE