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mitochondrial permeability transition

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2017
0102019992017

Related topics

Related topics

1 relation

Broader (1)

positive regulation of mitochondrial membrane permeability

Related mentions per year

Related mentions per year

1965-2018
1960198020002020
mitochondrial permeability transition
positive regulation of mitochondrial membrane permeability

Papers overview

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Review
2015
Review
2015
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition
The term mitochondrial permeability transition (MPT) is commonly used to indicate an abrupt increase in the permeability of the… (More)
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2008
2008
The identity and regulation of the mitochondrial permeability transition pore: where the known meets the unknown.
The mitochondrial permeability transition (MPT) pore complex is a key participant in the machinery that controls mitochondrial… (More)
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Highly Cited
2007
Highly Cited
2007
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death
Mitochondria are critically involved in necrotic cell death induced by Ca2+ overload, hypoxia and oxidative damage. The… (More)
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Highly Cited
2005
Highly Cited
2005
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death.
Mitochondria play an important role in energy production, Ca2+ homeostasis and cell death. In recent years, the role of the… (More)
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Highly Cited
2004
Highly Cited
2004
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore.
Environmental stresses converge on the mitochondria that can trigger or inhibit cell death. Excitable, postmitotic cells, in… (More)
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Highly Cited
2004
Highly Cited
2004
Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition.
Extensive activation of poly(ADP-ribose) polymerase-1 (PARP-1) by DNA damage is a major cause of caspase-independent cell death… (More)
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2003
2003
Cholesterol impairs the adenine nucleotide translocator-mediated mitochondrial permeability transition through altered membrane fluidity.
Mitochondrial permeability transition (MPT) has been proposed to play a key role in cell death. Downstream MPT events include the… (More)
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2001
2001
Calcium preconditioning inhibits mitochondrial permeability transition and apoptosis.
We tested the hypothesis whether calcium preconditioning (CPC) reduces reoxygenation injury by inhibiting mitochondrial… (More)
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2000
2000
Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides
Digitonin-permeabilized PC12 and GT1-7 neural cells exhibited a cyclosporin A-sensitive decrease in mitochondrial membrane… (More)
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Highly Cited
2000
Highly Cited
2000
Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition.
OBJECTIVE Diminishing oxidative stress may protect the heart against ischaemia-reperfusion injury by preventing opening of the… (More)
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