Skip to search formSkip to main contentSkip to account menu

mitindomide

Known as: 3a,3b,4,4a,7a,8a,8b-octahydro-4,8-ethenopyrrolo(3',4':3,4)cyclobut(1,2-f)isoindole-1,3,5,7(2H,6H)-tetrone, 4, 8-Ethenopyrrolo[3',4':3,4]cyclobut[1,2-f]isoindole-1,3,5,7(2H, 6H)tetrone, octahydro-, tricyclo(4.2.2.0(2,5))dec-9-ene-3,4,7,8-tetracarboxylic acid diimide 
A bisdioxopiperazines analog with antineoplastic activity. Mitinomide inhibits topoisomerase II and slowly promotes DNA-interstrand cross-linking… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Six novel high energy density compounds of N, N′-azobis-polynitrodiazoles were designed. Their optimized geometric and electronic… 
2012
2012
Synthesis of 1,8-dioxo-octahydroxanthene derivatives from dimedone and aldehydes using silica-supported phosphorus pentoxide (P… 
2008
2008
The extractives of Eucalyptus urophydis wood consumes more bleaching agents which seriously affect the quality of pulp and paper… 
2003
2003
The bisdioxopiperazines are catalytic inhibitors of eukaryotic type II DNA topoisomerases capable of trapping these enzymes as a… 
1997
1997
The antitumor drug mitindomide (NSC 284356) was shown to inhibit the decatenation activity of human and Chinese hamster ovary… 
1994
1994
We studied the liposome formulation characteristics of eight new lipophilic antitumour agents that have demonstrated a broad… 
1986
1986
Potential prodrugs of the highly insoluble, diimide antitumor agent mitindomide (1b) were synthesized by several different…