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mitiglinide

Known as: 2-benzyl-3-(hexahydro-2-isoindolinylcarbonyl)propionate, 2H-Isoindole-2-butanoic acid, octahydro-gamma-oxo-alpha-(phenylmethyl)-, calcium salt, (2(S)-cis)-, miti-glinide 
A succinic acid derivative with hypoglycemic activity. Like other meglitinide-type compounds, mitiglinide has a high affinity for SUR1 subunits.
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Hypoglycemic AgentsIsoindolesS21403

Narrower (1)

KAD 1229

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Tighter control of postprandial hyperglycemia with mitiglinide/voglibose fixed-dose combination in Japanese patients with type 2 diabetes mellitus
Objective: The objective of this study was to compare the effects of mitiglinide, voglibose and its combination on metabolic… 
Review
2010
Review
2010
Mitiglinide: A Novel Agent for the Treatment of Type 2 Diabetes Mellitus
Objective: To review the pharmacology, pharmacokinetics, efficacy, and safety of mitiglinide, a rapid-acting insulin secretion… 
2009
2009
Pleiotropic Effects of Mitiglinide in Type 2 Diabetes Mellitus
This study investigated the effects of mitiglinide in 16 patients with type 2 diabetes mellitus treated with 30 mg/day… 
2009
2009
Multicentre, Double-blind, Randomized Study of Mitiglinide Compared with Nateglinide in Type 2 Diabetes Mellitus Patients in China
This study investigated the non-inferiority of mitiglinide 10–20 mg versus nateglinide 120 mg, given orally three times daily for… 
2009
2009
Ancient Greek Hydromyths About the Submarine Transport of Terrestrial Fresh Water Through Seabeds Offshore of Karstic Regions
This study examined the relationship between ancient Greek texts and the physical possibility of focused, distal flow of… 
2007
2007
Nateglinide and Mitiglinide, but Not Sulfonylureas, Induce Insulin Secretion through a Mechanism Mediated by Calcium Release from Endoplasmic Reticulum
Nateglinide and mitiglinide (glinides) are characterized as rapid-onset and short-acting insulinotropic agents. Although both… 
2007
2007
Long-term effect of combination therapy with mitiglinide and once daily insulin glargine in patients who were successfully switched from intensive insulin therapy in short-term study.
We have previously reported the therapeutic efficacy of mitiglinide combined with once daily insulin glargine (mitiglinide… 
2006
2006
Therapeutic efficacy of mitiglinide combined with once daily insulin glargine after switching from multiple daily insulin regimen of aspart insulin and glargine in patients with type 2 diabetes…
Mitiglinide is novel class of rapid-acting insulin secretagogues, which have been widely used alone or in combination with other… 
Review
2003
Review
2003
Cardiovascular risk in type 2 diabetics and pharmacological regulation of mealtime glucose excursions.
Review
1999
Review
1999
Recent Developments and Emerging Therapies for Type 2 Diabetes Mellitus
Most patients with type 2 (non-insulin-dependent) diabetes mellitus require pharmacotherapy, initially as monotherapy and… 
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