mitiglinide

Known as: 2-benzyl-3-(hexahydro-2-isoindolinylcarbonyl)propionate, 2H-Isoindole-2-butanoic acid, octahydro-gamma-oxo-alpha-(phenylmethyl)-, calcium salt, (2(S)-cis)-, miti-glinide 
A succinic acid derivative with hypoglycemic activity. Like other meglitinide-type compounds, mitiglinide has a high affinity for SUR1 subunits.

Topic mentions per year

Topic mentions per year

1999-2017
051019992017

Papers overview

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2013
2013
INTRODUCTION The aim of this research was to compare the pharmacodynamics of the combination of mitiglinide and sitagliptin to… (More)
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2010
2010
OBJECTIVE Mitiglinide, a rapid- and short-acting insulinotropic sulfonylurea receptor ligand, exhibits hypoglycemic action unlike… (More)
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2010
2010
Mitiglinide is a rapid- and short-acting insulinotropic sulfonylurea receptor ligand and features rapid hypoglycemic action. To… (More)
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2009
2009
This study investigated the effects of mitiglinide in 16 patients with type 2 diabetes mellitus treated with 30 mg/day… (More)
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2007
2007
Diabetic patients often have manifestation of coronary heart disease. As a consequence, therapeutic strategies for diabetes… (More)
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2007
2007
Mitiglinide (MGN) is a new potassium channel antagonist for the treatment of type 2 diabetes mellitus. In the present study, a… (More)
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2006
2006
Mitiglinide is novel class of rapid-acting insulin secretagogues, which have been widely used alone or in combination with other… (More)
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2005
2005
Evidence suggests that postprandial hyperglycaemia may be a cardiovascular risk factor in diabetes. Oxidative stress and… (More)
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2001
2001
Mitiglinide (KAD-1229), a new anti-diabetic drug, is thought to stimulate insulin secretion by closing the ATP-sensitive K+ (K… (More)
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2001
2001
1. We have investigated the mechanism of action of the novel anti-diabetic agent mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2… (More)
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