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mithramycin A

National Institutes of Health

Papers overview

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2016
2016
Increasing evidence has shown that specificity protein 1 (Sp1) is abnormally increased in the brains of subjects with Alzheimer’s… 
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2014
2014
Cervical cancer is the third most common cancer and the third leading cause of death among women. However, the standard treatment… 
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2013
2013
In several human malignancies, overexpression of myeloid cell leukemia-1 (Mcl-1) confers resistance to induction of apoptosis… 
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Highly Cited
2013
Highly Cited
2013
The transcription factor specificity protein 1 (Sp1) plays a role in the development and progression of various types of human… 
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Highly Cited
2011
Highly Cited
2011
Both betulinic acid (BA) and mithramycin A (MIT) exhibit potent antitumor activity through distinct mechanisms of Sp1 inhibition… 
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2010
2010
Mithramycin A (MitA) is a chemotherapeutic compound which has been used in the therapy of several types of cancer. For… 
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2010
2010
Differential cleavage at three restriction enzyme sites was used to determine the specific binding to DNA of the antitumour… 
Highly Cited
2007
Highly Cited
2007
Human pancreatic cancer over expresses the transcription factor Sp1. However, the role of Sp1 in pancreatic cancer angiogenesis… 
2007
2007
The antitumour antibiotic mithramycin A (MTA) is a DNA minor-groove binding ligand. It binds to C/G-rich tracts as a dimer that… 
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