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mithramycin A

 
National Institutes of Health

Papers overview

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2014
2014
Cervical cancer is the third most common cancer and the third leading cause of death among women. However, the standard treatment… Expand
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2014
2014
DIG-MSK (demycarosyl-3D-β-D-digitoxosyl-mithramycin SK) is a recently isolated compound of the mithramycin family of antitumor… Expand
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2013
2013
Mithramycin A (Mith) is a natural polyketide that has been used in multiple areas of research including apoptosis of various… Expand
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2013
2013
In several human malignancies, overexpression of myeloid cell leukemia-1 (Mcl-1) confers resistance to induction of apoptosis… Expand
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Highly Cited
2013
Highly Cited
2013
The transcription factor specificity protein 1 (Sp1) plays a role in the development and progression of various types of human… Expand
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Highly Cited
2011
Highly Cited
2011
Both betulinic acid (BA) and mithramycin A (MIT) exhibit potent antitumor activity through distinct mechanisms of Sp1 inhibition… Expand
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2010
2010
Mithramycin A (MitA) is a chemotherapeutic compound which has been used in the therapy of several types of cancer. For… Expand
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2010
2010
Differential cleavage at three restriction enzyme sites was used to determine the specific binding to DNA of the antitumour… Expand
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Highly Cited
2007
Highly Cited
2007
Human pancreatic cancer over expresses the transcription factor Sp1. However, the role of Sp1 in pancreatic cancer angiogenesis… Expand
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2007
2007
The antitumour antibiotic mithramycin A (MTA) is a DNA minor-groove binding ligand. It binds to C/G-rich tracts as a dimer that… Expand
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