Skip to search formSkip to main contentSkip to account menu

miltefosine

Known as: hexadecyl 2-(trimethylazaniumyl)ethyl phosphate, n-hexadecylphosphorylcholine, Choline Phosphate Hexadecyl Ester, Hydroxide, Inner Salt 
An orally- and topically-active alkyl-phosphocholine compound with potential antineoplastic activity. Miltefosine targets cellular membranes… 
National Institutes of Health

Related topics

Related topics

11 relations

Broader (3)

Antifungal AgentsAntineoplastic AgentsPhosphorylcholine
Antiprotozoal AgentsLeishmaniasisNCIt Antineoplastic Agent Terminologyanalogs & derivatives

Narrower (3)

D 18506ImpavidoMiltex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2010
Review
2010
New antileishmanial candidates and lead compounds.
Review
2007
Review
2007
Rationale and clinical application of alkylphospholipid analogues in combination with radiotherapy.
Highly Cited
2003
Highly Cited
2003
Hydrosoluble formazan XTT: its application to natural products drug discovery for Leishmania.
Highly Cited
2001
Highly Cited
2001
Evaluation of shale and organoclays as sorbent additives for low-permeability soil containment barriers.
A natural shale and four synthetic organoclays were compared as potential sorbent additives to containment barriers at hazardous… 
Highly Cited
1999
Highly Cited
1999
Topical treatment with hexadecylphosphocholine (Miltex) efficiently reduces parasite burden in experimental cutaneous leishmaniasis.
Review
1998
Review
1998
Cytotoxic etherphospholipid analogues.
Highly Cited
1992
Highly Cited
1992
Hexadecylphosphocholine inhibits translocation of CTP:choline-phosphate cytidylyltransferase in Madin-Darby canine kidney cells.
Highly Cited
1991
Highly Cited
1991
The phospholipid analogue hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis in Madin—Darby canine kidney cells
Highly Cited
1991
Highly Cited
1991
The phospholipid analogue, hexadecylphosphocholine, inhibits protein kinase C in vitro and antagonises phorbol ester-stimulated cell proliferation.
Highly Cited
1987
Highly Cited
1987
Interaction of acyl coenzyme A substrates and analogues with pig kidney medium-chain acyl-coA dehydrogenase.
Several alkylthio coenzyme A (CoA) derivatives (from ethyl- to hexadecyl-SCoA) have been synthesized to probe the substrate… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)