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miglitol

Known as: Miglitolum, miglitol [Chemical/Ingredient], N-hydroxyethyl-1-desoxy-nojirimycin 
A desoxynojirimycin derivative and inhibitor of alpha-glucosidase with antihyperglycemic activity. Miglitol binds to and inhibits alpha-glucosidase… 
National Institutes of Health

Related topics

Related topics

16 relations

Broader (4)

1-DeoxynojirimycinEnzyme InhibitorsGlycoside Hydrolase InhibitorsHypoglycemic Agents
Congenital digestive system anomaliesDiabetes Mellitus, Non-Insulin-DependentDiabetic KetoacidosisDrug Allergy

Narrower (2)

DiastabolGlyset

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Rapid quantification of miglustat in human plasma and cerebrospinal fluid by liquid chromatography coupled with tandem mass spectrometry.
2008
2008
Comparison of pre‐ vs. postmeal administration of miglitol for 3 months in type 2 diabetic patients
Aim:  α‐Glucosidase inhibitors (αGIs) primarily modify postprandial plasma glucose levels and should be taken just before meals… 
2007
2007
Divided-dose administration of miglitol just before and 15 minutes after the start of a meal smoothes postprandial plasma glucose excursions and serum insulin responses in healthy men.
We recently demonstrated that administration of miglitol at 15 min after the start of a meal decreased the area under the curve… 
Review
2006
Review
2006
Tight control of hyperglycemia in type 2 diabetes mellitus
2004
2004
Miglitol may have a blood glucose lowering effect unrelated to inhibition of alpha-glucosidase
SummaryMiglitol is an alpha-glucosidase inhibitor which lowers blood glucose and insulin concentrations in healthy volunteers… 
2002
2002
Dose-dependent efficacy of miglitol, an alpha-glucosidase inhibitor, in type 2 diabetic patients on diet alone: results of a 24-week double-blind placebo-controlled study.
AIMS A double-blind randomised study was performed to compare the dose-effect and dose-tolerability relationships between the… 
Highly Cited
1998
Highly Cited
1998
Long‐term effectiveness of a new α‐glucosidase inhibitor (BAY m1099‐miglitol) in insulin‐treated Type 2 diabetes mellitus
In a double‐blind, randomized study, miglitol (BAY m 1099), an α‐glucosidase inhibitor, 100 mg tds or placebo was given orally… 
1998
1998
Long-term effectiveness of a new alpha-glucosidase inhibitor (BAY m1099-miglitol) in insulin-treated type 2 diabetes mellitus.
In a double-blind, randomized study, miglitol (BAY m 1099), an alpha-glucosidase inhibitor, 100 mg tds or placebo was given… 
1992
1992
α-Glucosidase Inhibition by Miglitol in NIDDM Patients
Objective To determine the efficacy of the α-glucosidase inhibitor miglitol (BAYm 1099) regarding the starch content of food… 
1988
1988
1-Deoxynojirimycin and related compounds inhibit glycogenolysis in the liver without affecting the concentration of phosphorylase a.
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