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midchain alkane hydroxylase activity

Catalysis of the conversion of an alkane to a secondary alcohol. [PMID:17905869]
National Institutes of Health

Papers overview

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2019
2019
Identification of 19-(S/R)Hydroxyeicosatetraenoic Acid as the First Endogenous Noncompetitive Inhibitor of Cytochrome P450 1B1 with Enantioselective Activity
The overexpression of cytochrome P450 1B1 (CYP1B1) is a common characteristic of several diseases and conditions, such as… Expand
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2018
2018
S-Enantiomer of 19-Hydroxyeicosatetraenoic Acid Preferentially Protects Against Angiotensin II-Induced Cardiac Hypertrophy
We had recently demonstrated that the racemic mixture of 19-hydroxyeicosatetraenoic acid (19-HETE) protects against angiotensin… Expand
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2014
2014
Characterization of Arachidonic Acid Metabolism by Rat Cytochrome P450 Enzymes: The Involvement of CYP1As
Cytochrome P450 (P450) enzymes mediate arachidonic acid (AA) oxidation to several biologically active metabolites. Our aims in… Expand
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2009
2009
Branched polymer-protein conjugates made from mid-chain-functional P(HPMA).
A novel midchain-functional chain transfer agent was synthesized and used as a reversible addition-fragmentation chain transfer… Expand
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Highly Cited
2004
Highly Cited
2004
Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1.
The cytochrome P450 family 1 (CYP1) is considered to be one of the xenobiotic-metabolizing enzyme families and is responsible for… Expand
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1999
1999
Biosynthesis of sialylated and fucosylated selectin ligands of HL-60 cells in vitro. Midchain alpha3-fucose units inhibit terminal alpha6-sialylation but not alpha3-sialylation of polylactosamines.
Polylactosamines Neu5Ac alpha2-3'Lex beta1-3'Lex beta1-3'Lex and Neu5Ac alpha2-3'LNbeta1-3'Lex beta1-3'Lex [Lex, Gal beta1-4(Fuc… Expand
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1998
1998
Arachidonic acid metabolism in the marine fish Stenotomus chrysops (Scup) and the effects of cytochrome P450 1A inducers.
Cytochrome P450-mediated arachidonic acid (AA) metabolism was investigated in the marine fish scup, Stenotomus chrysops. Liver… Expand
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1998
1998
Biosynthesis of Branched Polylactosaminoglycans
Two types of β1,6-GlcNAc transferases (IGnT6) are involved in in vitro branching of polylactosamines: dIGnT6 (distally acting… Expand
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1997
1997
Improved enzymatic synthesis of a highly potent oligosaccharide antagonist of L-selectin.
The polylactosamine sLex beta1-3'(sLex beta1-6')LacNAc beta1-3'(sLex beta1-6')LacNAc beta1-3'(sLex beta1-6')LacNAc (7) (where… Expand
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