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NMR spectroscopic analysis of exopolysaccharides produced by Leuconostoc citreum and Weissella confusa.
- N. Maina, M. Tenkanen, H. Maaheimo, R. Juvonen, L. Virkki
- Chemistry, Medicine
- Carbohydrate research
- 7 July 2008
Dextrans are the main exopolysaccharides produced by Leuconostoc species. Other dextran-producing lactic acid bacteria include Streptococci, Lactobacilli, and Weissella species. Commercial production… Expand
l‐galactonate dehydratase is part of the fungal path for d‐galacturonic acid catabolism
- Satu Kuorelahti, P. Jouhten, H. Maaheimo, M. Penttilä, P. Richard
- Chemistry, Biology
- Molecular microbiology
- 1 August 2006
An l‐galactonate dehydratase and the corresponding gene were identified from the mould Hypocrea jecorina (Trichoderma reesei). This novel enzyme converts l‐galactonate to l‐threo‐3‐deoxy‐hexulosonate… Expand
Structural analysis of enzyme-resistant isomaltooligosaccharides reveals the elongation of α-(1→3)-linked branches in Weissella confusa dextran.
- Ndegwa Henry Maina, L. Virkki, H. Pynnönen, H. Maaheimo, M. Tenkanen
- Chemistry, Medicine
- Biomacromolecules
- 5 January 2011
Weissella confusa VTT E-90392 is an efficient producer of a dextran that is mainly composed of α-(1→6)-linked D-glucosyl units and very few α-(1→3) branch linkages. A mixture of the Chaetomium… Expand
Complementary Acceptor and Site Specificities of Fuc-TIV and Fuc-TVII Allow Effective Biosynthesis of Sialyl-TriLex and Related Polylactosamines Present on Glycoprotein Counterreceptors of Selectins*
- R. Niemelä, J. Natunen, +5 authors R. Renkonen
- Chemistry, Medicine
- The Journal of Biological Chemistry
- 13 February 1998
The P-selectin counterreceptor PSGL-1 is covalently modified by mono α2,3-sialylated, multiply α1,3-fucosylated polylactosamines. These glycans are required for the adhesive interactions that allow… Expand
Acyl group migration and cleavage in selectively protected beta-d-galactopyranosides as studied by NMR spectroscopy and kinetic calculations.
- Mattias U. Roslund, O. Aitio, J. Wärnå, H. Maaheimo, D. Murzin, R. Leino
- Chemistry, Medicine
- Journal of the American Chemical Society
- 11 June 2008
The migration of acetyl, pivaloyl, and benzoyl protective groups and their relative stabilities at variable pH for a series of beta- d-galactopyranoses were studied by NMR spectroscopy. The clockwise… Expand
O-acetylation of glucuronoxylan in Arabidopsis thaliana wild type and its change in xylan biosynthesis mutants.
- Sun-Li Chong, L. Virkki, +8 authors M. Tenkanen
- Chemistry, Medicine
- Glycobiology
- 1 June 2014
O-Acetylglucuronoxylans (AcGX) in Arabidopsis thaliana carry acetyl residues on the 2-O and/or 3-O positions of the xylopyranosyl (Xylp) units, but the distribution of different O-acetylated Xylp… Expand
Hydrolysis of konjac glucomannan by Trichoderma reesei mannanase and endoglucanases Cel7B and Cel5A for the production of glucomannooligosaccharides.
- Atte Mikkelson, H. Maaheimo, Terhi K. Hakala
- Chemistry, Medicine
- Carbohydrate research
- 3 May 2013
In this paper we describe the enzymatic hydrolysis of konjac glucomannan for the production of glucomannooligosaccharides using purified Trichoderma reesei mannanase, endoglucanases EGI (Tr Cel7b)… Expand
Synthesis of a divalent sialyl Lewis x O-glycan, a potent inhibitor of lymphocyte-endothelium adhesion. Evidence that multivalency enhances the saccharide binding to L-selectin.
- H. Maaheimo, R. Renkonen, J. Turunen, L. Penttilä, O. Renkonen
- Chemistry, Medicine
- European journal of biochemistry
- 1 December 1995
The recognition of cell-surface L-selectin by its carbohydrate ligands causes lymphocytes to roll on capillary endothelium at sites of inflammation. As this primary contact is a prerequisite for… Expand
Synthesis of a new nanomolar saccharide inhibitor of lymphocyte adhesion: different polylactosamine backbones present multiple sialyl Lewis x determinants to L-selectin in high-affinity mode.
- O. Renkonen, S. Toppila, +6 authors R. Renkonen
- Medicine, Chemistry
- Glycobiology
- 1 June 1997
Lymphocyte infiltration is a hallmark of acute rejections in solid organ transplants, such as cardiac allograft. We have previously shown that lymphocyte extravasation to cardiac grafts undergoing… Expand
Functional expression of Pseudomonas aeruginosa GDP-4-keto-6-deoxy-D-mannose reductase which synthesizes GDP-rhamnose.
- M. Mäki, N. Järvinen, J. Räbinä, C. Roos, H. Maaheimo, R. Renkonen
- Biology, Medicine
- European journal of biochemistry
- 1 February 2002
Pseudomonas aeruginosa is an opportunistic Gram-negative bacterium that causes severe infections in a number of hosts from plants to mammals. A-band lipopolysaccharide of P. aeruginosa contains… Expand