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methylglyoxal biosynthetic process

Known as: methylglyoxal formation, methylglyoxal biosynthesis, methylglyoxal anabolism 
The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid. [GOC:ai]
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Laboratory kinetic and mechanistic studies on the OH-initiated oxidation of acetone in aqueous solution.
The OH-initiated oxidation of acetone in aqueous solution is investigated because of its potential implications in atmospheric… 
Highly Cited
2007
Highly Cited
2007
Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice.
To attain a profile of protein expression during diabetes, we applied proteomic analysis to glomeruli of 160-day-old db/db… 
Highly Cited
2006
Highly Cited
2006
Yeast protein glycation in vivo by methylglyoxal
Protein glycation by methylglyoxal is a nonenzymatic post‐translational modification whereby arginine and lysine side chains form… 
Highly Cited
2005
Highly Cited
2005
Measurement of methylglyoxal in rat tissues by electrospray ionization mass spectrometry and liquid chromatography.
Review
2002
Review
2002
Glycation in diabetic neuropathy: characteristics, consequences, causes, and therapeutic options.
Highly Cited
2001
Highly Cited
2001
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
The accumulation of triosephosphates and the increased formation of the potent glycating agent methylglyoxal in intracellular… 
2000
2000
Modulation of plasminogen activation and plasmin activity by methylglyoxal modification of the zymogen.
Highly Cited
1993
Highly Cited
1993
The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal.
In Krebs-Ringer phosphate buffer, the rate of formation of methylglyoxal from glycerone phosphate and glyceraldehyde 3-phosphate… 
Highly Cited
1992
Highly Cited
1992
Accumulation of S-D-lactoylglutathione and transient decrease of glutathione level caused by methylglyoxal load in isolated hepatocytes.
Highly Cited
1974
Highly Cited
1974
Accumulation of Toxic Concentrations of Methylglyoxal by Wild-Type Escherichia coli K-12
Wild-type strains of Escherichia coli K-12 accumulate toxic concentrations of methylglyoxal when grown in medium containing… 
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