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methyl-dehydroxymethyl-alpha-amanitin

 
National Institutes of Health

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1 relation
2-methyl-demethyl gamma-amanitin

Papers overview

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2012
2012
The novel NF-κB inhibitor DHMEQ synergizes with celecoxib to exert antitumor effects on human liver cancer cells by a ROS-dependent mechanism.
In a previous work of ours dehydroxymethyl-epoxyquinomicin (DHMEQ), an inhibitor of NF-κB, was shown to induce apoptosis through… Expand
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2008
2008
The Novel NF-κB Activation Inhibitor Dehydroxymethyl-Epoxyquinomicin Suppresses Anti-Thy1.1-Induced Glomerulonephritis in Rats
Abstract Background: NF-κB participates in the transcriptional regulation of numerous genes, and many studies have confirmed the… Expand
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2006
2006
A selective NFkappaB inhibitor, DHMEQ, reduced atherosclerosis in ApoE-deficient mice.
BACKGROUND AND PURPOSE Atherosclerosis is a chronic inflammatory process, and anti-inflammatory agents potentially inhibit the… Expand
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2006
2006
A Selective NFκB Inhibitor, DHMEQ, Reduced Atherosclerosis in ApoE-deficient mice
Background and Purpose: Atherosclerosis is a chronic inflammatory process, and anti-inflammatory agents potentially inhibit the… Expand
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2006
2006
Survivin associates with cell proliferation in renal cancer cells: regulation of survivin expression by insulin-like growth factor-1, interferon-gamma and a novel NF-kappaB inhibitor.
Although survivin has been widely recognized as an attractive target for cancer therapy, the exact mechanism regarding the… Expand
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2003
2003
Preparation of radioactively labeled dehydroxymethyl-epoxyquinomicin, an NF-kappa B function inhibitor.
Dehydroxymethylepoxyquinomicin (DHMEQ), a synthetic derivative of epoxyquinomicin C, is a potent and specific inhibitor of NF… Expand
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Review
2002
Review
2002
Molecular design and biological activities of NF-kappaB inhibitors.
NF-kappaB is a transcription factor that induces inflammatory cytokines and anti-apoptotic proteins. We designed a new NF-kappaB… Expand
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