methyl-(4-carboxyphenyl)glycine

Known as: MCPG cpd 
 
National Institutes of Health

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Broader (1)

Glycine
analogs & derivatives

Papers overview

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Highly Cited
2007
Highly Cited
2007
Absence of metabotropic glutamate receptor-mediated plasticity in the neocortex of fragile X mice.
Fragile X syndrome is a common heritable form of mental retardation in humans. Recent neuroanatomical studies indicate an… (More)
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2006
2006
Sustained activation of metabotropic glutamate receptor 5 and protein tyrosine phosphatases mediate the expression of (S)-3,5-dihydroxyphenylglycine-induced long-term depression in the hippocampal…
Previous studies have shown that brief application of group I metabotropic glutamate receptor (mGluR) agonist (S)-3, 5… (More)
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Highly Cited
2002
Highly Cited
2002
Dendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons.
Changes in the morphology of dendritic spines are correlated with synaptic plasticity and may relate mechanistically to its… (More)
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Highly Cited
1999
Highly Cited
1999
Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors.
Activation of metabotropic glutamate receptors (mGluRs) leads to modulation of a variety of second messenger pathways probably… (More)
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Highly Cited
1997
Highly Cited
1997
Group 1 and 2 metabotropic glutamate receptors play differential roles in hippocampal long-term depression and long-term potentiation in freely moving rats.
This study examined the role of metabotropic glutamate receptors (mGluRs) in hippocampal long-term depression (LTD) in vivo. The… (More)
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Highly Cited
1996
Highly Cited
1996
Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals.
A long-standing question in neurobiology is whether astrocytes respond to the neuronal release of neurotransmitters in vivo. To… (More)
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1996
1996
Contrast adaptation and excitatory amino acid receptors in cat striate cortex.
We have employed two paradigms to investigate the mechanisms of contrast gain control in cat striate cortex. In the first… (More)
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Highly Cited
1995
Highly Cited
1995
Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3.
1. The pharmacology of the metabotropic glutamate receptor (mGluR) that mediates synaptic depression at corticostriatal synapses… (More)
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1995
1995
Receptors and second messengers involved in long-term depression in rat cerebellar slices in vitro: a reappraisal.
In patch-clamped Purkinje cells (PCs), bath application of the ionotropic glutamate receptor antagonist, 6-cyano-7… (More)
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1994
1994
Induction of cerebellar long-term depression requires activation of glutamate metabotropic receptors.
In rat cerebellar slices, 500 microM (RS)-alpha-methyl-4-carboxyphenylglycine (MCPG) reversibly inhibited both dendritic and… (More)
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