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methasquin

Known as: N-(4-((2,4-diamino-5-methyl-6-quinazolinyl)methylamino)benzoyl)-L-aspartic acid 
National Institutes of Health

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2 relations

Broader (1)

Aspartic Acid
analogs & derivatives

Papers overview

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2006
2006
Disparate sensitivity of prostate cancer cell lines to antifolates
554 Success of antimetabolite chemotherapy in the treatment of metastatic prostate cancer has been extremely limited. The… 
1978
1978
Biochemical and karyological properties of cells resistant to the quinazoline antifolate, methasquin.
1975
1975
A basis for the difference in toxicity of methotrexate, aminopterin and methasquin in mice.
Highly Cited
1972
Highly Cited
1972
Two different species of dihydrofolate reductase in mammalian cells differentially resistant to amethopterin and methasquin.
The disparate cross-resistance behavior of certain amethopterin-resistant Chinese hamster cell lines to the quinazoline… 
Highly Cited
1972
Highly Cited
1972
Comparative studies on the transport of aminopterin, methotrexate, and methasquin by the L1210 leukemia cell.
Comparison was made of the uptake in L1210 leukemia cells of the agents aminopterin, methotrexate, and the quinazoline antifolate… 
1972
1972
Dihydrofolate Reductase Activity in Strains of Streptococcus faecium var. durans Resistant to Methasquin and Amethopterin
Resistance to the antifolates methasquin and amethopterin has been studied in new strains of Streptococcus faecium var. durans… 
1971
1971
Urinary and biliary excretion of the 2,4-diaminoquinazoline antifolate, methasquin, in rats and dogs.
The urinary and biliary excretion of methasquin [ N -{ p -{[(2,4-diamino-5-methyl-6-quinazolinyl) methyl]amino}benzoyl}-l… 
1971
1971
Toxicologic studies of the 2,4-diamino-quinazoline antifolate, methasquin (NSC-122870).
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