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mesenchymal stem cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that… (More)

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Topic mentions per year

1986-2017
010203019862017

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regulation of mesenchymal stem cell differentiation

Related mentions per year

Related mentions per year

1986-2018
19801990200020102020
mesenchymal stem cell differentiation
regulation of mesenchymal stem cell differentiation

Papers overview

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Highly Cited
2011
Highly Cited
2011
CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells
Enhancer of zeste homologue 2 (EZH2) is the catalytic subunit of Polycomb repressive complex 2 (PRC2) and catalyses the… (More)
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Highly Cited
2010
Highly Cited
2010
Direct and indirect effects of microstructured titanium substrates on the induction of mesenchymal stem cell differentiation towards the osteoblast lineage.
Microstructured and high surface energy titanium substrates increase osseointegration in vivo. In vitro, osteoblast… (More)
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Highly Cited
2010
Highly Cited
2010
The effect of matrix stiffness on mesenchymal stem cell differentiation in a 3D thixotropic gel.
Recent studies have demonstrated the effect of matrix stiffness on the phenotype and differentiation pathway of mesenchymal stem… (More)
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Highly Cited
2006
Highly Cited
2006
Intervertebral disc cell-mediated mesenchymal stem cell differentiation.
Low back pain is one of the largest health problems in the Western world today, and intervertebral disc degeneration has been… (More)
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Highly Cited
2006
Highly Cited
2006
The guidance of human mesenchymal stem cell differentiation in vitro by controlled modifications to the cell substrate.
Material-driven control of bone-marrow-derived mesenchymal stem cell (MSC) behaviour and differentiation is a very exciting… (More)
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2006
2006
Limitations of using aggrecan and type X collagen as markers of chondrogenesis in mesenchymal stem cell differentiation.
The study was initially designed to differentiate human bone marrow-derived mesenchymal stem cells (MSC) into chondrocyte-like… (More)
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Highly Cited
2005
Highly Cited
2005
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation.
Mesenchymal stem cells (MSCs) are a pluripotent cell type that can differentiate into several distinct lineages. Two key… (More)
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Highly Cited
2004
Highly Cited
2004
Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy.
OBJECTIVE Because mesenchymal stem cells can differentiate into chondrocyte-like cells, we ask the question, can mesenchymal stem… (More)
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Highly Cited
2000
Highly Cited
2000
Adult human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by mitogen-activated protein kinase.
Adult human mesenchymal stem cells are primary, multipotent cells capable of differentiating to osteocytic, chondrocytic, and… (More)
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Highly Cited
2000
Highly Cited
2000
Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model.
Bone marrow stromal cells can give rise to several mesenchymal lineages. The existence of a common stem/progenitor cell, the… (More)
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