mesalamine

Known as: Mesalazine, m Aminosalicylic Acid, 5 asa 
An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and… (More)
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Patients with ulcerative colitis and Crohn's disease are at increased risk for developing colorectal cancer (CRC). Chronic… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS SPD476 (LIALDA in the US; MEZAVANT in the EU; otherwise known as MMX mesalamine; Shire Pharmaceuticals Inc… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS SPD476 (MMX mesalamine), a novel, once-daily mesalamine formulation, uses MMX Multi Matrix System (MMX… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND AND PURPOSE Mesalamine is the first-line therapy for colitis, but it lacks potency and is only effective for mild-to… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND AND AIMS:Preliminary data have shown that delayed release oral mesalamine (Asacol®) dosed at 4.8 g/day provided… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS No therapy has been shown to reliably prevent the evolution of postoperative recurrence of Crohn's disease. The… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Because the reoperation rate for Crohn's disease is high after resective surgery, use of conservative surgery… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Epidermal growth factor (EGF) is a potent mitogenic peptide produced by salivary glands. We examined whether EGF… (More)
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Highly Cited
2001
Highly Cited
2001
AIM We evaluated the effect of coadministration of sulphasalazine, mesalamine, and balsalazide on the pharmacokinetics and… (More)
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Highly Cited
1993
Highly Cited
1993
The efficacy of a capsule formulation of mesalamine was assessed in 374 patients with mild to moderately active ulcerative… (More)
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