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mesalamine
Known as:
Mesalazine
, m Aminosalicylic Acid
, 5 asa
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An agent derived from sulfasalazine, an antiinflammatory agent. Mesalamine may reduce inflammation through inhibition of cyclooxygenase and…
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National Institutes of Health
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Related topics
Related topics
32 relations
24 HR mesalamine 375 MG Extended Release Oral Capsule [Apriso]
Aminosalicylic Acids
Drug Allergy
In Blood
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Narrower (11)
5-Aminosalicylate
Asacol
Asacolitin
Asacolon
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Broader (2)
Anti-Inflammatory Agents, Non-Steroidal
aminosalicylic acid
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
Clostridium Difficile Infection—An Unusual Cause of Refractory Pouchitis: Report of a Case
S. Mann
,
J. Pitt
,
R. Springall
,
A. Thillainayagam
Diseases of the Colon & Rectum
2003
Corpus ID: 22517645
AbstractPURPOSE: Ileal pouch-anal anastomosis is the surgical procedure of choice for selected patients with severe ulcerative…
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Highly Cited
2001
Highly Cited
2001
A new 5-aminosalicylic acid multi-unit dosage form for the therapy of ulcerative colitis.
M. Rudolph
,
S. Klein
,
T. Beckert
,
Hans-Ulrich Petereit
,
J. Dressman
European journal of pharmaceutics and…
2001
Corpus ID: 25831431
Highly Cited
2000
Highly Cited
2000
Probiotics for ulcerative colitis therapy: Rembacken BJ, Snelling AM, Hawkey PM, et al. Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: A randomized trial…
D. Mack
2000
Corpus ID: 71254335
Highly Cited
1996
Highly Cited
1996
Mesalamine in Crohn's disease with steroid-induced remission: effect on steroid withdrawal and remission maintenance, Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives.
R. Modigliani
,
J. Colombel
,
+12 authors
J. Mary
Gastroenterology
1996
Corpus ID: 40118293
BACKGROUND & AIMS Steroid dependence and early relapse are frequent after a prednisolone-induces remission in Crohn's disease…
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Highly Cited
1991
Highly Cited
1991
Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease.
S. Schreiber
,
R. Macdermott
,
A. Raedler
,
R. Pinnau
,
M. Bertovich
,
G. S. Nash
Gastroenterology
1991
Corpus ID: 33031664
Highly Cited
1987
Highly Cited
1987
Effect of sulphasalazine and its metabolites on the generation of reactive oxygen species.
Y. Miyachi
,
A. Yoshioka
,
S. Imamura
,
Y. Niwa
Gut
1987
Corpus ID: 27145265
The relative in vitro anti-oxidant efficacy of sulphasalazine (salicylazosulphapyridine, SASP) and its metabolites (5…
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Highly Cited
1987
Highly Cited
1987
Actions of sulfasalazine and 5-aminosalicylic acid as reactive oxygen scavengers in the suppression of bile acid-induced increases in colonic epithelial cell loss and proliferative activity.
P. Craven
,
James Pfanstiel
,
Reisuke Saito
,
F. Derubertis
Gastroenterology
1987
Corpus ID: 28133790
Highly Cited
1985
Highly Cited
1985
Which component of sulphasalazine is active in rheumatoid arthritis?
T. Pullar
,
J. Hunter
,
H. Capell
British medical journal
1985
Corpus ID: 20266948
Sulphasalazine is known to be effective as a second line agent in the treatment of rheumatoid arthritis. The two chemical…
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Highly Cited
1980
Highly Cited
1980
Effect of sulphapyridine, 5-aminosalicylic acid, and placebo in patients with idiopathic proctitis: a study to determine the active therapeutic moiety of sulphasalazine.
P. van Hees
,
J. H. Bakker
,
J. V. van Tongeren
Gut
1980
Corpus ID: 19468656
Suppositories of sulphapyridine, 5-aminosalicylic acid, and placebo were used in 45 patients with idiopathic proctitis to…
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Highly Cited
1972
Highly Cited
1972
Nephrotoxic Lesions from 5-Aminosalicylic Acid
I. Calder
,
C. Funder
,
C. R. Green
,
K. Ham
,
J. Tange
British medical journal
1972
Corpus ID: 29631250
5-Aminosalicylic acid given to rats as a single intravenous injection led to necrosis of the proximal convoluted tubules and of…
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