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meisoindigo

National Institutes of Health

Papers overview

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2013
2013
[Mechanism about therapeutic effect of meisoindigo on psoriasis via down-regulation of the TLR4-TAK-NF-kappaB pathways].
Meisoindigo is an indigo natural derivative commonly used in anti-cancer therapy. In the clinical application, it was also found… 
2010
2010
[Effect of Meisoindigo on Wnt signal pathway in K562 and HL-60 cells].
The aim of this study was to investigate the effect of meisoindigo on Wnt signal pathway in K562 cells and HL-60 cells and its… 
2009
2009
Identification of metabolites of meisoindigo in rat, pig and human liver microsomes by UFLC-MS/MS.
2008
2008
Identification of Stereoisomeric Metabolites of Meisoindigo in Rat Liver Microsomes by Achiral and Chiral Liquid Chromatography/Tandem Mass Spectrometry
N-Methylisoindigotin, abbreviated as meisoindigo, has been a routine therapeutic agent in the clinical treatment of chronic… 
2008
2008
Characterization of metabolites of meisoindigo in male and female rat kidney microsomes by high-performance liquid chromatography coupled with positive electrospray ionization tandem mass…
Meisoindigo has been effectively applied for the treatment of chronic myelogenous leukemia (CML). Although the metabolic profile… 
2005
2005
[Inducement effect of Meisoindigo on apoptosis of leukemia cell line HL-60 and its mechanism].
BACKGROUND & OBJECTIVE Meisoindigo is a powerful drug used in treating chronic myeloid leukemia (CML), but little is known about… 
2005
2005
Meisoindigo in Combination with Imatinib Accelerates Apoptosis of K562 Cells
Objective To investigate whether imatinib in combination with meisoindigo can accelerate apoptosis of K562 cells. Methods After… 
1999
1999
Apoptosis inducing effect of meisoindigo on K562 Cells
OBJECTIVE To study the effect of meisoindigo on human chronic myelogenous leukemia (CML) cell line K562 cells for exploring the… 
1991
1991
Pharmacological studies of meisoindigo: absorption and mechanism of action.
Meisoindigo, an indirubin derivative, is a new type of cancer chemotherapeutic agent. It exhibited higher activity against rodent… 
1990
1990
[Screening for in vitro metabolites of meisoindigo using RP-HPLC-DAD with gradient elution].
A method of screening for in vitro metabolites of meisoindigo using RP-HPLC-DAD (photodiode array detector) with gradient elution… 
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