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meiotic recombination checkpoint

Known as: pachytene checkpoint 
A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed… 
National Institutes of Health

Papers overview

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2015
2015
Dynamics of Sun5 Localization during Spermatogenesis in Wild Type and Dpy19l2 Knock-Out Mice Indicates That Sun5 Is Not Involved in Acrosome Attachment to the Nuclear Envelope
The acrosome is an organelle that is central to sperm physiology and a defective acrosome biogenesis leads to globozoospermia, a… 
2008
2008
The fission yeast meiotic checkpoint kinase Mek1 regulates nuclear localization of Cdc25 by phosphorylation
In eukaryotic cells, fidelity in transmission of genetic information during cell division is ensured by the action of cell cycle… 
2004
2004
The Signal from the Initiation of Meiotic Recombination to the First Division of Meiosis
ABSTRACT Two of the unique events that occur in meiosis are high levels of genetic recombination and the reductional division… 
2003
2003
Regulation of meiotic progression by the meiosis-specific checkpoint kinase Mek1 in fission yeast
During the eukaryotic cell cycle, accurate transmission of genetic information to progeny is ensured by the operation of cell… 
2003
2003
Activity of phosphoforms and truncated versions of Ndt80, a checkpoint-regulated sporulation-specific transcription factor of Saccharomyces cerevisiae
Ndt80 contributes to the highly regulated cascade of sequential gene expression that directs spore formation in Saccharomyces… 
Highly Cited
2002
Highly Cited
2002
A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint.
The pachytene checkpoint prevents meiotic cell cycle progression in response to unrepaired recombination intermediates. We show… 
2002
2002
Synaptic behaviour and morphological modifications of the X and Y chromosomes during pachytene in three species of Ctenomys (Rodentia, Caviomorpha, Ctenomyidae).
Synaptic behaviour and the progression of morphological differentiation of the XY chromosome pair during pachytene was studied… 
2001
2001
Replication protein A is sequentially phosphorylated during meiosis.
Phosphorylation of the cellular single-stranded DNA-binding protein, replication protein A (RPA), occurs during normal mitotic… 
Highly Cited
2000
Highly Cited
2000
The pachytene checkpoint prevents accumulation and phosphorylation of the meiosis-specific transcription factor Ndt80.
In budding yeast, many mutants defective in meiotic recombination and chromosome synapsis undergo checkpoint-mediated arrest at… 
Highly Cited
1999
Highly Cited
1999
Genetic control of recombination partner preference in yeast meiosis. Isolation and characterization of mutants elevated for meiotic unequal sister-chromatid recombination.
Meiotic exchange occurs preferentially between homologous chromatids, in contrast to mitotic recombination, which occurs… 
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