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megakaryocyte development

Known as: megakaryocyte cell development 
The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte… 
National Institutes of Health

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Megakaryocyte Differentiation

Papers overview

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Review
2010
Review
2010
Apoptotic processes in megakaryocytes and platelets.
It is becoming increasingly clear that most mammalian cells are capable of undergoing apoptosis and that, within particular… 
2000
2000
Recombinant human interleukin-11 synergizes with steel factor and interleukin-3 to promote directly the early stages of murine megakaryocyte development in vitro.
The authors studied the role that interleukin (IL)-11 plays during the early stages of megakaryocyte (MK) development by… 
1999
1999
Selective modulation of the cyclin B/CDK1 and cyclin D/CDK4 complexes during in vitro human megakaryocyte development
Mammalian megakaryocyte development is characterized by a progressive accumulation of cells exhibiting a polylobated nucleus with… 
1998
1998
Cyclin D3 and megakaryocyte development: Exploration of a transgenic phenotype
The roles of cell cycle regulatory proteins in megakaryocyte development are poorly understood. We have previously demonstrated… 
Review
1994
Review
1994
The mpl ligand: molecular and cellular biology of the critical regulator of megakaryocyte development.
The development of blood cells requires the interplay of hematopoietic stem and progenitor cells, marrow stroma and polypeptide… 
Review
1993
Review
1993
Population heterogeneity among cells of the megakaryocyte lineage
Understanding the developmental steps in megakaryocyte differentiation requires information regarding the microenvironmental… 
1991
1991
Recombinant human granulocyte-macrophage colony-stimulating factor promotes megakaryocyte maturation in nonhuman primates.
Megakaryocytes are responsive to several nonlineage-specific cytokines in vitro. In this study, we examined the in vivo effects… 
1988
1988
ANALYSIS OF PHORBOL ESTER STIMULATED HUMAN MEGAKARYOCYTE DEVELOPMENT
The events that occur during the terminal maturation of human megakaryocytes are poorly characterized. To examine these events, a… 
1985
1985
Immune regulation of in vitro murine megakaryocyte development. Role of T lymphocytes and Ia antigen expression
Mitogen-activated murine T lymphocytes or T cell hybridomas produce an activity (megakaryocyte [Mk] potentiator activity) that… 
1974
1974
Changes in Megakaryocyte Development Following Thrombocytopenia
Summary. Rats were made thrombocytopenic by total‐body X‐irradiation and changes in megakaryocyte development studied in shielded… 
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