Megakaryocyte Differentiation

Known as: megakaryocyte cell differentiation 
The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. [GOC:mah]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1975-2017
0102019752017

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2011
2011
Dasatinib is a novel, potent, ATP-competitive inhibitor of Bcr-Abl, cKIT, and Src family kinases that exhibits efficacy in… (More)
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2007
2007
Polyploidization is a part of the normal developmental process leading to platelet production during megakaryocyte (MK… (More)
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2006
2006
A major determinant in platelet production is the megakaryocyte (MK) size that is regulated both by ploidization and the increase… (More)
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2003
2003
OBJECTIVE Megakaryopoiesis is characterized by two major processes, acquisition of lineage-specific markers and polyploidization… (More)
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2001
2001
It is shown that the tetraspanin CD9 has a complex pattern of distribution in hematopoietic cells and is heterogeneously… (More)
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2000
2000
GATA-1 and GATA-2 transcription factors are required for effective hematopoiesis. These regulatory proteins present overlapping… (More)
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Highly Cited
1999
Highly Cited
1999
Thrombopoietin (TPO) plays a critical role in megakaryocyte proliferation and differentiation. Using various cultured cell lines… (More)
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Highly Cited
1998
Highly Cited
1998
During megakaryocyte differentiation, the promegakaryoblast (immature megakaryocyte) increases its ploidy to a 2(x) DNA content… (More)
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Highly Cited
1997
Highly Cited
1997
The K562 erythroleukemia cell line was used to study the molecular mechanisms regulating lineage commitment of hematopoietic stem… (More)
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1995
Highly Cited
1995
GATA-1 is a zinc-finger transcription factor believed to play an important role in gene regulation during the development of… (More)
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