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matriptase 2

Known as: matriptase-2, matriptase-2, human 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Membrane ProteinsSerine Endopeptidases
TMPRSS6 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2
Matriptase-2 is a type II transmembrane serine protease and a key regulator of systemic iron homeostasis. Since the activation… 
2017
2017
Design and chemical syntheses of potent matriptase‐2 inhibitors based on trypsin inhibitor SFTI‐1 isolated from sunflower seeds
Matriptase‐2 plays a pivotal role in keeping iron concentrations within a narrow physiological range in humans. The opportunity… 
2017
2017
Current status of iron metabolism: Clinical and therapeutic implications
2016
2016
Evaluation of bisbenzamidines as inhibitors for matriptase-2.
2016
2016
Matriptase-2 links erythropoietin to iron.
In this issue of Blood,Nai et al demonstrate that the serine protease matriptase-2 mediates erythropoietin (EPO)-dependent… 
2015
2015
Cell surface serine protease matriptase-2 suppresses fetuin-A/AHSG-mediated induction of hepcidin
Abstract Matriptase-2 is a type II transmembrane serine protease controlling the expression of hepcidin, the key regulator of… 
2014
2014
Substrate specificity of human matriptase-2.
2013
2013
Hepatocyte growth factor activator inhibitor type 2 (HAI-2) modulates hepcidin expression by inhibiting the cell surface protease matriptase-2.
Matriptase-2, a recently identified cell surface protease, is the key enzyme of iron homoeostasis modulating the expression of… 
2012
2012
Matriptase-2 (TMPRSS6) is directly up-regulated by hypoxia inducible factor-1: identification of a hypoxia-responsive element in the TMPRSS6 promoter region
Abstract The type II transmembrane serine protease matriptase-2 (TMPRSS6) down-regulates the expression of hepcidin, the main… 
2012
2012
The influence of matriptase-2 on prostate cancer in vitro: a possible role for β-catenin.
The type II transmembrane serine proteases (TTSPs) are a family of cell surface proteolytic enzymes contributing to a… 
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