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malagashanine

 
National Institutes of Health

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1 relation

Broader (1)

Alkaloids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Glutathione transferase from Plasmodium falciparum – Interaction with malagashanine and selected plant natural products
A glutathione transferase (PfGST) isolated from Plasmodium falciparum has been associated with chloroquine resistance. A range of… Expand
2006
2006
Malagashanine potentiates chloroquine antimalarial activity in drug resistant Plasmodium malaria by modifying both its efflux and influx.
Malagashanine (MG) is the parent compound of the new N(b)-C(21) seco-curan alkaloids isolated hitherto from Madagascan Strychnos… Expand
Review
2006
Review
2006
Medicinal and Aromatic Plant Science and Biotechnology
This review covers the general area of disease and problems such as malaria, bacterial and fungal infections, free radical damage… Expand
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2001
2001
Biological activities of the plant‐derived bisindole voacamine with reference to malaria
The in vivo antiplasmodial activity of voacamine was assessed in a 4‐day test. It was shown to exhibit in vivo activity with 25.4… Expand
2000
2000
Reversal activity of the naturally occurring chemosensitizer malagashanine in Plasmodium malaria.
Malagashanine (MG) is the parent compound of a new type of indole alkaloids, the N(b)C(21)-secocuran, isolated so far from the… Expand
2000
2000
Isolation from rat urine and human liver microsomes and identification by electrospray and nanospray tandem mass spectrometry of new malagashanine metabolites.
Malagashanine has been isolated from indigenous madagascan Strychnos myrtoides alkaloids used traditionally to treat malaria… Expand
2000
2000
High-performance liquid chromatographic assay of malagashanine in rat plasma and urine and its pharmacokinetic application.
A reversed-phase HPLC method was developed for quantitative analysis of malagashanine in rat plasma and urine. Malagashanine and… Expand
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1999
1999
Effects of the naturally-occurring chemosensitizer malagashanine and its combination with chloroquine on KB and P388 cell lines and isolated auricle.
Besides the determination of its LD50 value, the cytotoxicity against KB and P388 cell lines and the toxicity on isolated guinea… Expand
Review
1996
Review
1996
[Recent results on the pharmacodynamics of Strychnos malgaches alkaloids].
Investigation of Strychnos (Loganiaceae) shrubs and trees was initiated by their traditional uses of their inherent poisons on… Expand
Highly Cited
1994
Highly Cited
1994
In vitro and in vivo chloroquine-potentiating action of Strychnos myrtoides alkaloids against chloroquine-resistant strains of Plasmodium malaria.
Crude alkaloids of Strychnos myrtoides Gilg & Busse, empirically used as an adjuvant to chloroquine (CQ) in Malagasy herbal… Expand
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