major vault protein

Known as: Lung Resistance-Related Protein, MVP 
Major vault protein (893 aa, ~100 kDa) is encoded by the human MVP gene. This protein plays a role in both the structure and function of vault… (More)
National Institutes of Health

Papers overview

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2016
2016
Major vault protein forms a hollow, barrel-like structure in the cell called the vault, whose functions and regulation are not… (More)
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2015
2015
Senescence is a prominent solid tumor response to therapy in which cells avoid apoptosis and instead enter into prolonged cell… (More)
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2013
2013
Vaults are very large oligomeric ribonucleoproteins conserved among a variety of species. The rat vault 3D structure shows an… (More)
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2009
2009
During interphase growth of eukaryotic cells, nuclear pore complexes (NPCs) are continuously incorporated into the intact nuclear… (More)
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2008
2008
The planarian Schmidtea mediterranea and the cnidarian Hydra vulgaris have emerged as valuable model organisms in regeneration… (More)
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2006
2006
We have recently shown in MCF-7 cells that nuclear phosphatase and tensin homologue deleted on chromosome 10 (PTEN) down… (More)
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2006
2006
Vaults are abundant large ribonucleoprotein particles. They frequently colocalize with microtubules and accumulate in filamentous… (More)
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2002
2002
Breast cancer resistance protein (BCRP/ABCG2) is a novel member of ATPbinding cassette transporters, which induce multidrug… (More)
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1998
1998
Multidrug resistant cancer cells frequently overexpress the 110-kd lung resistance-related protein (LRP) as detected with the… (More)
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Highly Cited
1996
Highly Cited
1996
Multidrug resistance (MDR) to anticancer drugs is a major cause of treatment failure in cancer. The lung resistance protein LRP… (More)
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