mRNA Degradation

Known as: mRNA catabolic process, mRNA catabolism, Degradation, mRNA 
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
MicroRNAs (miRNAs) silence the expression of target genes post-transcriptionally. Their function is mediated by the Argonaute… (More)
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Highly Cited
2006
Highly Cited
2006
As an important mode of suppressing gene expression, messenger RNAs containing an AU-rich element (ARE) in the 3' untranslated… (More)
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Highly Cited
2005
Highly Cited
2005
MicroRNAs (miRNAs) are approximately 22 nucleotide RNAs that negatively regulate the expression of protein-coding genes. In a… (More)
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Highly Cited
2005
Highly Cited
2005
Small RNAs, including small interfering RNAs (siRNAs) and microRNAs (miRNAs) can silence target genes through several different… (More)
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Highly Cited
2005
Highly Cited
2005
Translation and mRNA degradation are affected by a key transition where eukaryotic mRNAs exit translation and assemble an mRNP… (More)
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Highly Cited
1999
Highly Cited
1999
Double-stranded RNA (dsRNA) directs gene-specific, post-transcriptional silencing in many organisms, including vertebrates, and… (More)
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Review
1999
Review
1999
Messenger RNAs in prokaryotes exhibit short half-lives when compared with eukaryotic mRNAs. Considerable progress has been made… (More)
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Highly Cited
1998
Highly Cited
1998
Double-stranded RNA (dsRNA) recently has been shown to give rise to genetic interference in Caenorhabditis elegans and also is… (More)
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Highly Cited
1995
Highly Cited
1995
Labile mRNAs that encode cytokine and immediate-early gene products often contain AU-rich sequences within their 3' untranslated… (More)
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Highly Cited
1993
Highly Cited
1993
We have examined the mechanism of thalidomide inhibition of lipopolysaccharide (LPS)-induced tumor necrosis factor alpha (TNF… (More)
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