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lumefantrine

Known as: 9H-Fluorene-4-methanol, 2,7-dichloro-9-((4-chlorophenyl)methylene)-alpha-((dibutylamino)methyl)-, (Z)-, dl-Benflumelol, 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (3)

AntimalarialsEthanolaminesFluorenes

Narrower (1)

Coartem
Malariaartemether / lumefantrineartemether 20 MG / lumefantrine 120 MG Oral Tabletartemether 20 MG / lumefantrine 120 MG Oral Tablet [Coartem]

Papers overview

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Highly Cited
2013
Highly Cited
2013
The Role of Pfmdr1 and Pfcrt in Changing Chloroquine, Amodiaquine, Mefloquine and Lumefantrine Susceptibility in Western-Kenya P. falciparum Samples during 2008–2011
Single Nucleotide Polymorphisms (SNPs) in the Pfmdr1, and Pfcrt, genes of Plasmodium falciparum may confer resistance to a number… 
Review
2009
Review
2009
Impact of the large-scale deployment of artemether/lumefantrine on the malaria disease burden in Africa: case studies of South Africa, Zambia and Ethiopia
Malaria is one of the most significant causes of morbidity and mortality worldwide. Every year, nearly one million deaths result… 
Highly Cited
2009
Highly Cited
2009
Probing the multifactorial basis of Plasmodium falciparum quinine resistance: evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE.
Highly Cited
2009
Highly Cited
2009
A single LC-tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma.
Highly Cited
2006
Highly Cited
2006
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
The global dissemination of drug-resistant Plasmodium falciparum is spurring intense efforts to implement artemisinin (ART)-based… 
Highly Cited
2000
Highly Cited
2000
Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine.
Highly Cited
2000
Highly Cited
2000
Pharmacokinetic interaction trial between co-artemether and mefloquine.
Highly Cited
1999
Highly Cited
1999
Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria.
Highly Cited
1998
Highly Cited
1998
Randomized Comparison of Artemether-Benflumetol and Artesunate-Mefloquine in Treatment of MultidrugResistant Falciparum Malaria
ABSTRACT An open, randomized comparison of artemether-benflumetol (CGP 56 697; Novartis) with artesunate-mefloquine was conducted… 
Review
1995
Review
1995
Status of antimalarial drugs under development.
Despite the urgent need of a new antimalarial drugs, particularly those against multiresistant falciparum malaria, only a limited… 
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