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lumefantrine

Known as: 9H-Fluorene-4-methanol, 2,7-dichloro-9-((4-chlorophenyl)methylene)-alpha-((dibutylamino)methyl)-, (Z)-, dl-Benflumelol, 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (3)

AntimalarialsEthanolaminesFluorenes

Narrower (1)

Coartem
Malariaartemether / lumefantrineartemether 20 MG / lumefantrine 120 MG Oral Tabletartemether 20 MG / lumefantrine 120 MG Oral Tablet [Coartem]

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2013
Review
2013
Artemether and lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in sub-Saharan Africa
Introduction: WHO Treatment Guidelines recommend that artemisinin-based combination therapies (ACTs) are used to treat… 
2012
2012
Large differences in prevalence of Pfcrt and Pfmdr1 mutations between Mwanza, Tanzania and Iganga, Uganda-a reflection of differences in policies regarding withdrawal of chloroquine?
Highly Cited
2011
Highly Cited
2011
In Vitro Activity of Proveblue (Methylene Blue) on Plasmodium falciparum Strains Resistant to Standard Antimalarial Drugs
ABSTRACT The geometric mean 50% inhibitory concentration (IC50) for Proveblue, a methylene blue complying with the European… 
2004
2004
Campaign to fight malaria hit by surge in demand for medicine
Drug shortfall undermining efforts to reduce death toll. 
Review
2001
Review
2001
Chemotherapeutic approaches to protozoa: Haemosporina – current level of knowledge and outlook
Chloroquine and mefloquine are available for prophylactic treatment in malaria, against a background of the burgeoning problem of… 
2001
2001
Desbutyl-Benflumetol, a Novel Antimalarial Compound: In Vitro Activity in Fresh Isolates of Plasmodium falciparumfrom Thailand
ABSTRACT Desbutyl-benflumetol (DBB) is a novel antimalarial compound closely related to benflumetol (lumefantrine), of which it… 
Highly Cited
1999
Highly Cited
1999
Multiple dose pharmacokinetics of artemether in Chinese patients with uncomplicated falciparum malaria.
1997
1997
Phase II trial in China of a new, rapidly-acting and effective oral antimalarial, CGP 56697, for the treatment of Plasmodium falciparum malaria.
One hundred and two Chinese out-patients with naturally acquired, previously untreated, falciparum malaria were selected to… 
Highly Cited
1996
Highly Cited
1996
Determination of a new antimalarial drug, benflumetol, in blood plasma by high-performance liquid chromatography.
Highly Cited
1996
Highly Cited
1996
Determination of benflumetol in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection.
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