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lobaplatin

Known as: 1,2-diaminomethylcyclobutane-platinum(II) lactate, 1,2-diammino-methy lcyclobutane-platinum (II) lactate 
A third-generation, water-soluble platinum compound with potential antineoplastic activity. Lobaplatin forms highly reactive, charged, platinum… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

CyclobutanesOrganoplatinum Compounds

Narrower (1)

D 19466
NCIt Antineoplastic Agent Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
A phase I clinical trial of dose escalation of lobaplatin in combination with fixed-dose docetaxel for the treatment of human solid tumours that had progressed following chemotherapy
In this study, the maximum tolerated dose (MTD) of lobaplatin (LBP) when it was combined with docetaxel (TXT) for the treatment… 
2011
2011
[Iridoid glycosides from buds of Jasminum officinale L. var. grandiflorum].
The study on the buds of Jasminum officinale L. var. grandiflorum was carried out to look for anti-HBV constituents. The… 
2004
2004
A Clinical Screening Cooperative Group phase II evaluation of lobaplatin (ASTA D-19466) in advanced head and neck cancer
SummaryWe evaluated the efficacy and tolerability of lobaplatin, a new platinum compound, given at the dose of 50 mg/m2 by i.v… 
Review
2003
Review
2003
Lobaplatin: D 19466.
Lobaplatin [D 19466] is a platinum complex with DNA alkylating activity that was developed by ASTA Medica (Degussa) for the… 
2002
2002
Lobaplatin as an adjuvant chemotherapy to surgery in canine appendicular osteosarcoma: a phase II evaluation.
Canine osteosarcoma, the most common bone tumor in dogs, is a well-established, naturally-occurring animal model for human OS… 
2002
2002
Synthesis of isoacteoside, a dihydroxyphenylethyl glycoside
The total chemical synthesis of isoacteoside (1), 2-(3′,4′-dihydroxyphenyl)ethyl 6-O-caffeoyl-3-O-(α-l-rhamnopyranosyl)-β-d… 
1995
1995
A trial of lobaplatin (D-19466) in platinum-resistant ovarian cancer.
Long-term survival in epithelial ovarian cancer remains problematic despite multimodality therapy. A fundamental difficulty is… 
1995
1995
Induction of the c-myc but not the cH-ras promoter by platinum compounds.
1992
1992
Pharmacokinetic and Pharmacodynamic Study with Lobaplatin (D-19466), a New Platinum Complex, after Bolus Administration
Background: Lobaplatin (D-19466) is a platinum compound with greater anticancer activity in NSCLC, stomach, breast and ovarian… 
1991
1991
Lipase-catalyzed triglyceride hydrolysis in organic solvent
  • A. BilykRaymond G. BistlineM. HaasStephen H. Feairheller
  • 1991
  • Corpus ID: 84472526
An investigation of lipases fromRhizomucor miehei,Candida rug osa and porcine pancreas revealed that these enzymes hydrolyzed… 
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