lobaplatin

Known as: 1,2-diaminomethylcyclobutane-platinum(II) lactate, 1,2-diammino-methy lcyclobutane-platinum (II) lactate 
A third-generation, water-soluble platinum compound with potential antineoplastic activity. Lobaplatin forms highly reactive, charged, platinum… (More)
National Institutes of Health

Papers overview

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2014
2014
AIM To assess the anti-cancer effect of lobaplatin on human gastric cancer cells, and to explore the underlying molecular… (More)
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2013
2013
AIMS To explore efficacy and side effects of intrapleural or intraperitoneal lobaplatin for treating patients with malignant… (More)
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2013
2013
PURPOSE This phase II study was undertaken to determine the efficacy and safety of Loubo® (Lobaplatin) in combination with… (More)
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2011
2011
Lobaplatin, as the third-generation platinum antineoplastic agent, showed promising antineoplastic effects in variety of… (More)
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Highly Cited
2010
Highly Cited
2010
Since its approval in 1979 cisplatin has become an important component in chemotherapy regimes for the treatment of ovarian… (More)
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Review
2001
Review
2001
Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes containing a 1,2-bis(aminomethyl)cyclobutane stable… (More)
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1997
1997
The cytotoxicity of cisplatin and cisplatin-DNA adduct formation in vitro and in vivo is clearly enhanced by hyperthermia. We… (More)
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1996
1996
Two interesting representatives of a new generation of platinum-based cytostatic drugs that are currently being tested in… (More)
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1995
1995
In phase I studies, lobaplatin showed activity in ovarian cancer patients pretreated with platinum. A phase II trial with… (More)
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Highly Cited
1992
Highly Cited
1992
The role of glutathione (GSH) in the effectiveness of and resistance to 7 platinum compounds [5 Pt(II) and 2 Pt(IV) drugs] was… (More)
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