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Phase II study of intravenous topotecan as a 5-day infusion for refractory epithelial ovarian carcinoma.
PURPOSE To determine the efficacy and toxicity of topotecan administered as a 5-day intravenous infusion in patients with advanced ovarian cancer refractory to cisplatin-based chemotherapy. Expand
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Extramammary Paget's disease of the perineal skin: role of radiotherapy.
We have reviewed our treatment results in 65 patients with extramammary Paget's disease arising in the vulva, perianal area, or scrotum. In 30 patients with primary disease, positive surgical marginsExpand
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Didelphic uterus and obstructed hemivagina with renal agenesis: case report and review of the literature.
Congenital disorders of development are more common than previously reported and the correct diagnosis is frequently missed leading to suboptimal treatment. Eight cases of uterus didelphys withExpand
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Secondary cytoreductive surgery for recurrent epithelial ovarian cancer.
Thirty patients with recurrent epithelial ovarian carcinoma who underwent secondary tumor-reductive surgery at M. D. Anderson Cancer Center were studied retrospectively. All had been initiallyExpand
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Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice.
The C57BL/6 (B6) mouse is more sensitive to the effects of a high-fat diet than the A/J strain. The B6 mouse develops severe obesity, hyperglycemia, and hyperinsulinemia when fed this dietaryExpand
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A dynamic test of lower extremity function following anterior cruciate ligament reconstruction and rehabilitation.
It is essential to assess the functional status of patients with surgically reconstructed and rehabilitated anterior cruciate ligaments prior to discharge. This study established a testing paradigmExpand
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Phase II study of irinotecan in prior chemotherapy-treated squamous cell carcinoma of the cervix.
PURPOSE A phase II study was performed to evaluate the antitumor activity and toxicity of irinotecan (CPT-11), a water-soluble derivative of camptothecin, in patients with prior chemotherapy-treatedExpand
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Recombinant Human Thrombopoietin Attenuates Carboplatin-Induced Severe Thrombocytopenia and the Need for Platelet Transfusions in Patients with Gynecologic Cancer
Myelosuppression is a serious complication in patients who are receiving chemotherapy for cancer. The use of myeloid growth factors has reduced the incidence of febrile neutropenia (1, 2). However,Expand
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Estrogen and progesterone receptor titers in primary epithelial ovarian carcinomas
Only 69% (42 of 61) of the documentated ovarian tumor specimens received between September 1981 and August 1982 contained 75% or more viable tumor. Of the 42 measured for estrogen receptors (ER) andExpand
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Clinical and biological effects of intraperitoneal injections of recombinant interferon-gamma and recombinant interleukin 2 with or without tumor-infiltrating lymphocytes in patients with ovarian or
To identify strategies that enhance tumor-specific immunity in patients with ovarian carcinoma, 22 patients received four to six doses of i.p. recombinant IFN-gamma (rIFN-gamma), 200 microg/m2 onExpand
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