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lithocholate 6beta-hydroxylase activity

Known as: cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase activity, lithocholate 6beta-monooxygenase activity, lithocholate,NADPH:oxygen oxidoreductase (6beta-hydroxylating) activity 
Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+). [EC:1.14.13.94, RHEA:18860]
National Institutes of Health

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CYP3A10 activity

Papers overview

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1995
1995
Intestinal absorption of lithocholate and its sulfate and glucuronide in rats
The absorption of lithocholate and its sulfate and glucuronide in rat jejunum and terminal ileum was studied. Tracer amounts of… 
1983
1983
Bile acid inhibition of basic and neutral glutathione S-transferases in rat liver.
A purification scheme is described for the neutral glutathione S-transferases of rat liver. Discontinuous sodium dodecyl sulphate… 
1982
1982
Lithocholate Sulphation in the Baboon
The site and extent of lithocholate sulphation have been examined in the baboon using labelled lithocholate. The liver is the… 
1980
1980
Development of enzymatic conjugation and sulfation of bile acids in hamster liver.
In vitro levels of enzyme activity were measured in liver from fetal and developing hamsters to study the fetal immaturity and… 
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