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lipoprotein receptor-related protein 6

Known as: Low Density Lipoprotein Receptor-Related Protein 6, Low Density Lipoprotein Receptor Related Protein 6, Low Density Lipoprotein Receptor-Related Protein-6 
An LDL-receptor related protein that combines with cell surface FRIZZLED RECEPTORS to form WNT PROTEIN-binding receptors. The protein plays an… 
National Institutes of Health

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In BloodLRP6 geneagonistsantagonists & inhibitors

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LRP6 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
A Role for Low-Density Lipoprotein Receptor-Related Protein 6 in Blood Vessel Regression in Wound Healing.
Objective: The healing of skin wounds is typified by a pattern of robust angiogenesis followed by vascular regression. Pigment… 
Review
2017
Review
2017
Wnt signaling in the vessel wall
Purpose of review Wnt signaling plays a crucial role during embryogenesis. In an adult, Wnt is mainly associated to cellular… 
2017
2017
Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation
A computational analysis of the X‐ray structure of the low‐density lipoprotein receptor‐related protein 6 (LRP6) with the… 
2014
2014
Fiber Type-Specific Expression of Low-Density Lipoprotein Receptor-Related Protein 6 in Human Skeletal Muscles
Objective: Gene expression patterns differ in the two types of skeletal muscle fiber. The Wnt signaling pathway, which includes… 
2014
2014
Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling
Cardiac side population cells (CSPs) are promising cell resource for the regeneration in diseased heart as intrinsic cardiac stem… 
2013
2013
Role of the Rap2/TNIK kinase pathway in regulation of LRP6 stability for Wnt signaling.
Highly Cited
2011
Highly Cited
2011
LRP6 Mediates cAMP Generation by G Protein–Coupled Receptors Through Regulating the Membrane Targeting of Gαs
The receptor LRP6 associates with Gαs to promote cAMP signaling by various GPCRs. Unexpected Partner Signaling by heterotrimeric… 
2010
2010
Amer 1 / WTX couples Wnt-induced formation of PtdIns ( 4 , 5 ) P 2 to LRP 6 phosphorylation
As you can see the referees appreciate the finding that Amer1 regulates LRP6 phosphorylation and beta-catenin signaling and find… 
2007
2007
Requirement for natively unstructured regions of mesoderm development candidate 2 in promoting low-density lipoprotein receptor-related protein 6 maturation.
Proteins of the low-density lipoprotein receptor family (LRPs) are complex, multimodular type I transmembrane receptors… 
2007
2007
Regulated proteolytic processing of LRP6 results in release of its intracellular domain
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a member of low‐density lipoprotein receptor (LDLR) family which… 
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